CAS: 17132-78-4; Pyridine-2,3-Dicarbonitrile

该化合物是一种七环有机化合物,其特点是在2和3个位置用两个环形组以两个环形组替代的核核心.这种结构具有高度的再活性,使它成为有机合成中有价值的中间体,特别是用于建造含氮的异性循环.其电子缺乏的性质有利于核生殖替代和循环反应,有利于在制药,农用化学品和材料科学方面的应用.该化合物的稳定性和与各种反应条件的兼容性增强了其在多步合成中的实用性.此外,其硬性芳香框架有助于开发光学材料的同质系统. Pyridine-2,3-二碳氢化合物由于其多功能性和功能性群体容忍性,在研究和工业环境中被广泛使用.

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上下游产品

3-cyanopyridine N-oxide trimethylsilyl cyanide sodium cyanidepyridine-3-carbonitrile 2-(pyrrolidin-1-yl)nicotinonitrile 2-isopropylamino-nicotinonitrile 6-(isopropylamino)nicotinonitrile

合成工艺路线路线简述

    📜5-Chloro-8-Hydrazinopyrido<2,3-D>Pyridazine置于ammonium Cerium (Iv) Nitrate体系中,用 甲醇 用作溶剂,以70%的收率获得吡啶-2,3-二甲腈
    参考文献:Can-Mediated Oxidation Of Electron-Deficient Aryl And Heteroaryl Hydrazines And Hydrazides
    标题:Can-Mediated Oxidation Of Electron-Deficient Aryl And Heteroaryl Hydrazines And Hydrazides
    摘要:芳基和杂芳基肼及肼酰胺成功地通过can被氧化,生成去肼化产物.反应途径强烈依赖于底物的性质,导致烃或烷氧衍生物的形成.当使用氘化溶剂,如氘代甲醇(methanol-D₄)或氘代乙腈(acetonitrile-D₃)时,实现了氘的区域特异性结合.
    Doi:10.1055/s-2007-1072749

    海关参考信息

    专利信息


    专利号:US-2006183758-A1
    优先权日:2005-02-17
    标 题:Method for synthesis of AZA-annelated pyrroles, thiophenes, and furans
    发明人:BEARD CHARLES D; LEE VING J; WHITTLE C E
    权利人:CB RES AND DEV INC
    摘要:Methods of synthesis of intermediates that are useful as bioisosteres of the indole, benzofuran and benzothiophene scaffold are disclosed.

    专利号:US-2020398222-A1
    优先权日:2019-06-14
    标题 :Control of composite covalent organic framework by varying functional groups inside the pore
    发明人:LI-OAKEY KATIE DONGMEI; HOBERG JOHN; PARKINSON BRUCE ALAN
    权利人:UNIV WYOMING
    摘要:An ordered functional nanoporous material (OFMN) composition includes a pore defined by a sidewall, the sidewall comprising N—C—N linkages therein. A process for synthesis of a reagent includes the reaction of a 6,7-diaminoquinoxaline having R groups with hexaketocyclohexane (HKH) octahydrate, where R is independently in each occurrence H, Cl, Br, I, C4H4S (thiophenyl), SO3−, CO2−, C≡CH, CHâ•?CH2, NH2, OH, C≡N, C1-C4 alkyl, (CH2)xCHâ•?CH2, or (CH2)yCHâ•?CH(CH2)z where x or (y+z) is an integer of 0 to 4 inclusive, (CH2)jCH≡CH, or (CH2)kCH≡C(CH2)r where j or (k+r) 0 to 4 inclusive. A process of degasification that includes extracting a gas from a mixture by exposing the mixture to an OFNM to selectively pass the gas therethrough. A process of dehydrogenation includes exposing an aliphatically unsaturated feedstock to platinum modified OFNM under conditions to form hydrogen and selectively passing the hydrogen through the platinum modified OFNM.

    专利号:CN-102775346-A
    优先权日:2012-08-24
    标题:A Bifunctional Basic Ionic Liquid and Its Aqueous Phase Catalytic Synthesis of Substituted Pyridines

    专利号:CN-103980193-A
    优先权日:2014-05-27
    标 题 :One-pot synthesis of 2, 6-diamino-3, 5-dicyanopyridine compound

    专利号:CN-103980193-B
    优先权日:2014-05-27
    标 题 :One-pot Synthesis of 2,6-Diamino-3,5-Dicyanopyridine Compounds

    专利号:CH-291803-A
    优先权日:1949-08-25
    标 题 :Process for the preparation of an intermediate product of the phthalocyanine synthesis.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Lou, S.; Zhang, J., Science of Synthesis Knowledge Updates, (2012) 2, 255.
    摘要:Rodríguez-Morgade, M. S.; Torres, T., Science of Synthesis Knowledge Updates, (2017) 2, 103.
    参考文献:10.1155/2008/392090
    摘要:Sakamoto K, Ohno-Okumura E, Kato T, Watanabe M, Cook MJ. Investigation of Zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) Porphyrazine for Application as Photosensitizer in Photodynamic Therapy of Cancer. Met Based Drugs. 2008;2008():392090.
    参考文献:10.2478/v10007-008-0005-4
    摘要:Hosni HM, Abdulla MM. Anti-inflammatory and analgesic activities of some newly synthesized pyridinedicarbonitrile and benzopyranopyridine derivatives. Acta Pharm. 2008 Jun;58(2):175–86. doi: 10.2478/v10007-008-0005-4.
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