CAS: 158932-33-3; (2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-(((2R,3R)-2,3-Bis(4-Hydroxy-3-Methoxybenzyl)Butane-1,4-Diyl)Bis(Oxy))Bis(2-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol)
该化合物是一种主要在亚麻籽和其他植物来源中发现的来自离子体的化合物,它因其作为诸如肠道醇和肠内醇等肠道阳素的前体的作用而得到承认,这些前体具有植物性能和抗氧化性特性.(R,R) 立体化学在其生物相互作用中赋予特殊性,增强了其在代谢和药理学研究方面的研究潜力.由于这种化合物的稳定性,水溶性(属于采石场生物)和生物利用率,使其适合于对食用性生殖剂和生物医学影响进行调查,因此具有意义,其明确界定的结构使得在营养学和生物医学研究中可以进行精确的分析应用.
- 英文名称(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-(((2R,3R)-2,3-Bis(4-Hydroxy-3-Methoxybenzyl)Butane-1,4-Diyl)Bis(Oxy))Bis(2-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol)
- 中文名称2,3-双(3-甲氧基-4-羟基苄基)丁烷-1,4-二醇 1,4-二葡萄糖甙
- IUPAC名称(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-(((2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butane-1,4-diyl)bis(oxy))bis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol)
- 其它别名b-D-Glucopyranoside,2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediyl bis-, [R-(R*,R*)]-; SDG; Secoisolariciresinol diglucoside; Secoisolariciresinol diglycoside
- CAS编号158932-33-3
- MFCD编号:MFCD03427692
- FDA UNII编号:T9281L29MV
- 分子式:C32H46O16分子量:686.7
- 产品CID: 794238
- 产品分类Chemistry → Asymmetric Synthesis → Chiral Building Blocks | Benzene Compounds | Tetrahydropyrans | Inhibitors/Agonists → GPCR/G Protein → PAFR | Inhibitors/Agonists → Immunology/Inflammation → ROS | Ethers | Alcohols
物理性质
MSDS等安全信息
上下游产品
88H78O24C88H78O24 88H78O24C88H78O24合成工艺路线路线简述
专利信息
专利号:US-12036300-B2
优先权日:2021-03-31
标题:Methods and compositions for improving skin
发明人：LIAO I-CHIEN; BRIEVA PATRICIA; JUCHAUX FRANCK; BOUEZ CHARBEL; ZHENG QIAN; QIAN KUN
权利人:OREAL
摘要:A method for managing skin tone comprising reducing the synthesis of melanin by applying a skin treatment composition to skin. The skin treatment composition may include about 0.1 to about 25 wt. % of acetyl trifluoromethylphenyl valylglycine; about 0.5 to about 30 wt. % of a polyol; about 0.1 to about 30 wt. % of a silicone, fatty compound, or a mixtures thereof, wherein the skin treatment composition is an emulsion, and all weight percentages are based on the total weight of the skin treatment composition.
专利号:CN-114478664-A
优先权日:2022-03-03
标题 :Chemical synthesis method of trans-ferulic acid-4-glucoside
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
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主要参考文献
1: Pietrofesa RA, Velalopoulou A, Albelda SM, Christofidou-Solomidou M. Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605). Int J Mol Sci. 2016 Mar 1;17(3):322. doi: 10.3390/ijms17030322.
2: Tan ZJ, Wang CY, Yang ZZ, Yi YJ, Wang HY, Zhou WL, Li FF. Ionic Liquid-Based Ultrasonic-Assisted Extraction of Secoisolariciresinol Diglucoside from Flaxseed (Linum usitatissimum L.) with Further Purification by an Aqueous Two-Phase System. Molecules. 2015 Sep 30;20(10):17929-43. doi: 10.3390/molecules201017929. Review. doi: 10.1093/carcin/bgv174.
5: Velalopoulou A, Tyagi S, Pietrofesa RA, Arguiri E, Christofidou-Solomidou M. The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage. Int J Mol Sci. 2015 Dec 22;17(1). pii: E7. doi: 10.3390/ijms17010007.
合成参考文献
参考文献:10.1038/s41592-019-0358-2]
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