CAS: 1441670-89-8; (S)-Tert-Butyl 6-(5-(7-Bromo-9,9-Difluoro-9H-Fluoren-2-yl)-1H-Imidazol-2-yl)-5-Azaspiro[2.4]Heptane-5-Carboxylate

相似化合物

2004675-25-4 1256388-50-7

上下游产品

(6S)-5-[(tert-butoxy)carbonyl]-5-azaspiro[2.4]heptane-6-carboxylic acid [1-(hydroxymethyl)cyclopropyl]methanol 1,1-bis(iodomethyl)cyclopropane cyclopropane-1,1-diylbis(methylene) dimethanesulfonatemethyl [(2S)-1-{(6S)-6-[5-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-azabicyclo[2.2.1]-hept-3-yl]-1H-benzimidazol-6-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl}-3-methyl-1-oxobutan-2-yl]carbamate (1-{3-[6-(9,9-difluoro-7-{2-[5-(2-methoxycarbonylamino-3-methyl-butyryl)-5-aza-spiro[2.4]hept-6-yl]-3H-imidazol-4-yl}-9H-fluoren-2-yl)-1H-benzoimidazol-2-yl]2-aza-bicyclo[2.2.1]heptane-2-carbonyl}-2-methyl-propyl)carbamicacid methyl ester D-tartrate salt (1-{6-[5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-aza-spiro[2.4]heptane-5-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester

专利信息

专利号:US-9718807-B2
优先权日:2012-06-05
标 题 :Synthesis of antiviral compound
发明人：SCOTT ROBERT WILLIAM; VITALE JUSTIN PHILIP; MATTHEWS KENNETH STANLEY; TERESK MARTIN GERALD; FORMELLA ALEXANDRA; EVANS JARED WAYNE
权利人:GILEAD PHARMASSET LLC
摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates to compounds of formula I.

专利号:US-2015232453-A1
优先权日:2012-06-05
标 题 :Synthesis of antiviral compound

专利号:US-2016340345-A1
优先权日:2012-06-05
标题 :Synthesis of antiviral compound

专利号:EP-2855454-B1
优先权日:2012-06-05
标 题 :Synthesis of antiviral compound

专利号:US-9056860-B2
优先权日:2012-06-05
标题:Synthesis of antiviral compound