CAS: 129714-97-2; 3,5-Difluorobenzoyl Chloride

该化合物是一种芳香化合物,其特点是氟原子和丙基氯的功能组同时存在,在3和5个位置上有一个以两个氟原子替代的苯环,以及直接附于氯原子(Cl)的碳基(C=O)组.这一结构具有独特的化学特性,包括氟原子和丙基氯的功能产生的电子脱衣效应,增加了活性.该化合物一般是淡黄色液体的无色,呈现出一种发光的气味.它溶于二氯乙烷和乙醚等有机溶剂中,但与水发生反应,释放盐酸并形成相应的碳白酸.3,5-二氟苯基氯在有机合成中被使用,特别是用于制作各种药品和农用化学物,因为其能够作为乙基剂.在处理这一化合物时,必须采取安全防范措施,因为接触时可能会具有腐蚀性和有害性.

英文名称3,5-Difluorobenzoyl Chloride
中文名称3,5-二氟苯甲酰氯
IUPAC名称3,5-difluorobenzoyl chloride
其它别名3,5-Difluorobenzenecarbonylchloride; 3,5-Difluorobenzoyl chloride
CAS编号129714-97-2
MFCD编号:MFCD00010309
EINECS号:627-835-9
分子式:C7H3ClF2O
分子量:176.55
产品CID: 456828
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考;;;
InChIKey: OYZWEOORLJBPMA-UHFFFAOYSA-N
InChI=1S/C7H3ClF2O/c8-7(11)4-1-5(9)3-6(10)2-4/h1-3H…
计算化学: 氢键受体数3.0氢键供体数0.0可旋转键数1.0

相似化合物

1711-07-5 177787-26-7 76903-88-3

MSDS等安全信息

GHS象形图
GHS符号GHS07 & GHS05;
注释: Exclamation mark & Corrosion
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀类别1B
严重眼刺激类别2
金属腐蚀物类别1
严重眼损伤类别1
警示词Danger(危险)
危险描述H335 |可能引起呼吸道刺激.
H314 |造成严重皮肤灼伤和眼损伤.
H319 |造成严重眼刺激.
H290 |可能对金属造成腐蚀.
H318 |造成严重眼损伤.
防范说明P210-P261-P264-P271-P280-P301+P330+P331-P303+P361+P353-P363-P370+P378-P403+P233-P403+P235-P405-P501
危险等级8
UN编号3265.0
危险品标志C
风险等级Corrosive
包装等级Ⅱ
安全声明23-26-27-36/37/39-45
危险类别码34-36/37
WGK Germany3

欧盟法规

ECHA物质C&L通报

上下游产品

合成工艺路线路线简述

合成目标产物 3,5-Difluorobenzoyl Chloride 主要起始原料 3,5-Difluorobenzoic Acid
(文献来源)合成步骤主要原料 3,5-Difluorobenzoic Acid

3,5-二氟苯甲酸置于草酰氯体系中,化学反应生成3,5-二氟苯甲酰氯
参考文献:使用弱配位导向基团的铜介导的(杂)芳烃的c H硫醇化
标题:使用弱配位导向基团的铜介导的(杂)芳烃的c H硫醇化
摘要:通过使用单齿酰胺作为弱配位导向基团,我们开发了铜介导的(杂)芳烃的c H硫醇化反应.该方案具有出色的官能团耐受性,并与各种杂环(如吲哚,吡咯,咪唑,吡啶,噻吩和喹啉)具有令人满意的相容性.该协议的鲁棒性使其在合成应用中具有潜在价值.
Doi:10.1016/j.Tetlet.2020.152062

海关参考信息

2912110000-甲醛
2912210000-苯甲醛
2903110000-一氯甲烷及氯乙烷
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

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权利人:MOMENTIVE PERFORMANCE MAT GMBH
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