CAS: 915922-38-2; (3-Chloro-4-Ethoxyphenyl)Methanol

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3-chloro-4-methoxy-benzaldehyde methylmagnesium chloride 4-ethoxy-3-chloro-benzaldehyde

📜3-氯-4-乙氧基苯甲醛 以100%的收率获得产物(3-氯-4-乙氧基苯)甲醇
参考文献: Inhibitors Of Acetyl-Coa Carboxylase[fr] Inhibiteurs De L'Acétyl-Coa Carboxylase
标题: Inhibitors Of Acetyl-Coa Carboxylase[fr] Inhibiteurs De L'Acétyl-Coa Carboxylase
摘要:本发明涉及作为乙酰辅酶a羧化酶(acc)抑制剂的化合物.该发明还涉及制备这些化合物的方法,含有这些化合物的组合物,以及使用这些化合物进行治疗的方法.

专利信息

专利号:US-4477660-A
优先权日:1982-11-16
标 题 :7-(S)-Acylaminocephalosporin sulfones and process
发明人：HALL DAVID A
权利人:LILLY CO ELI
摘要:This invention encompasses 7-(S)-acylamino-3-acetoxymethyl-3-cephem-4-carboxylic acid sulfones and the epimerization process for making them. The epimerization process employs an organic nitrogen base reagent having a pKa between about 9.0 to about 11.5. The compounds of this invention are intermediates in the synthesis of 1-oxa-β-lactam antibiotics.

专利号:US-4459405-A
优先权日:1982-11-16
标 题 :Desacetylcephalosporin sulfones
发明人：HALL DAVID A
权利人:LILLY CO ELI
摘要:7-(S)-Acylamino-3-hydroxymethyl-3-cephem sulfones are disclosed. These compounds are intermediates in the synthesis of 1-oxa β-lactam antibiotics.

专利号:US-4474879-A
优先权日:1982-11-16
标 题 :Process for 3-hydroxymethyl cephalosporin sulfones
发明人：HEINEY RICHARD E
权利人:LILLY CO ELI
摘要:This invention relates to a process for preparing 7-(S)-acylamino-3-hydroxymethyl-3-cephem-4-carboxylic acid sulfones and the salts and esters thereof. The instant process involves contacting a 7-(S)-acylamino-3-acetoxymethyl cephalosporin sulfone in an aqueous solution buffered from about pH 6 to about pH 8 with citrus acetylesterase, which is immobilized on silica gel. The 3-hydroxymethyl cephalosporin sulfones produced by the process of this invention are intermediates in the synthesis of 1-oxa β-lactam antibiotics.