CAS: 25186-47-4; 3,5-Dichlorotoluene

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CAS号99520-05-5 2,6-二氯-4-甲基-苯甲酸 | CAS号69380-94-5 3,5-Dichlorbenz... | CAS号100-52-7 苯甲醛 | CAS号100-39-0 溴化苄 | CAS号30273-00-8 2,4-二氯-6-甲基苯胺 | CAS号19393-93-2 2-溴-1,3-二氯-5-甲基苯 | CAS号99500-35-3 2-氯-4-甲基苯甲酸乙酯 | CAS号94-08-6 对甲基苯甲酸乙酯 | CAS号120-66-1 乙酰邻甲苯胺 | CAS号61655-97-8 2,4-二氯-6-甲基乙酰苯胺 | CAS号50-73-7 2,3,5-三氯苯甲酸 | CAS号51719-65-4 3,5-二氯苯乙酸 | CAS号51-36-5 3,5-二氯苯甲酸 | CAS号99519-84-3 羧基酰胺 | CAS号2905-62-6 3,5-二氯苯甲酰氯 | CAS号52516-37-7 2-(3,5-二氯苯基)乙腈 | CAS号118665-00-2 3,5-二氯-2-硝基甲苯 | CAS号2905-67-1 3,5-二氯苯甲酸甲酯 | CAS号7778-01-0 3,5-二氯苄基溴 | CAS号99520-05-5 2,6-二氯-4-甲基-苯甲酸

对甲基苯甲酸乙酯置于sodium Persulfate,N-氯代丁二酰亚胺,三氟甲磺酸,Palladium Diacetate,Silver Carbonate,Potassium Hydroxide体系中,用 甲醇,二甲基亚砜,1,2-二氯乙烷 用作溶剂,化学反应 38.0H,反应生成3,5-二氯甲苯
参考文献:区域和化学选择性c 弱配位的h氯化/缺电子芳烃的溴化和相对方向基团能力的研究
标题:区域和化学选择性c 弱配位的h氯化/缺电子芳烃的溴化和相对方向基团能力的研究
摘要:都是相对的:已经开发了一种实用而有效的pd Ii催化的区域和化学选择性氯化/溴化反应,可轻松合成各种芳族氯化物.该反应显示出优异的反应活性,非常好的官能团耐受性和高收率.进行了一项初步研究,以评估各种功能的相对指导能力.
Doi:10.1002/anie.201300176

专利信息

专利号:US-7148356-B2
优先权日:2001-07-13
标题:Process for the catalytic synthesis of biaryls and polymers from aryl compounds
发明人：SMITH III MILTON R; MALECZKA ROBERT E
权利人:UNIV MICHIGAN STATE
摘要:A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO 2 CF 3 ), or nonaflate (OSO 2 C 4 F 9 ). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds.

专利号:US-8163955-B2
优先权日:2008-12-18
标 题 :Process for the synthesis of 2,6-diamino-3,5-dinitrotoluene
发明人：DHAWAN RAJIV; RITTER JOACHIM C
权利人:DHAWAN RAJIV; RITTER JOACHIM C; DU PONT
摘要:An improved process is provided for the preparation of 2,6-diamino-3,5-dinitrotoluene by amination of 2,6-dichloro-3,5-dinitrotoluene. The presence of water unexpectedly results in a highly pure product, free of glycol ether impurities. This product can be used to make highly pure 2,3,5,6-tetraaminotoluene, which in turn can be used to make high molecular weight polybenzimidazoles for high strength fibers.

专利号:US-6828466-B2
优先权日:2002-07-19
标题:Process for the synthesis of phenols from arenes
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL; SHI FENG
权利人:UNIV MICHIGAN STATE
摘要:A process to synthesize substituted phenols such as those of the general formula RR'R''Ar(OH) wherein R, R', and R'' are each independently hydrogen or any group which does not interfere in the process for synthesizing the substituted phenol including, but not limited to, halo, alkyl, alkoxy, carboxylic ester, amine, amide; and Ar is any variety of aryl or hetroaryl by means of oxidation of substituted arylboronic esters is described. In particular, a metal-catalyzed C-H activation/borylation reaction is described, which when followed by direct oxidation in a single or separate reaction vessel affords phenols without the need for any intermediate manipulations. More particularly, a process wherein Ir-catalyzed borylation of arenes using pinacolborane (HBPin) followed by oxidation of the intermediate arylboronic ester by OXONE is described.

专利号:US-7074837-B2
优先权日:2000-08-08
标题 :Processes for preparation of bicyclic compounds and intermediates therefor
发明人：NAKAYAMA KEIJI; MUTO MAKOTO; SAITO TATSURU; TANI YUICHIRO; AKIBA TOSHIFUMI
权利人:DAIICHI SEIYAKU CO
摘要:A process for preparing intermediate compound (VII), compound (VIII) and compound (XIV) which will be raw materials for the synthesis of a synthetic antibactrial compound, via compound (I) or compound (X) and then, compound (II), the compounds each being shown below; and novel compounds useful for the preparation.

专利号:WO-2021143617-A1
优先权日:2020-01-16
标题 :Cyclohexadiene oxime ether compound, synthesis method therefor and application thereof
发明人：DENG ZHAOXI; Hu Hewei; GUO SHAOXIONG; CEN JIN; TAN BIN; DU BINGBING; YANG LINA; LI JUNPEI
权利人:ZHENGZHOU INSTITUTE OF CHIRAL DRUGS RES CO LTD
摘要:The present invention provides a cyclohexadiene oxime ether compound having the following structural formula: (I) or (II) or (III); group R 1 and group R 3 are each selected from -H, an aliphatic substituent containing 1-6 carbon atoms, a halogenated aliphatic substituent, a cyano-substituted aliphatic substituent, amino or amide, phenyl, and a halogenated aromatic substituent or a cyano-substituted aromatic substituent; group R 2 is selected from -H, an aliphatic substituent containing 1-6 carbon atoms, a halogenated aliphatic substituent, a cyano-substituted aliphatic substituent, amino or amide, phenyl, a halogenated aromatic substituent, and a cyano-substituted aromatic substituent, a nitro-substituted aromatic substituent or a heterocyclic aromatic substituent; and the heterocyclic aromatic substituent is selected from (iv), (v) or (vi), wherein X is selected from -H, halogen, -CN, -NO 2 , and -CF 3 , -C(CF 3 ) 3 , and n is the number of substituents and is selected from 1, 2, and 3. The present invention also provides a preparation method for the above-mentioned cyclohexadiene oxime ether compound and an application thereof.

专利号:US-7329769-B2
优先权日:2001-07-13
标 题:Catalytic boronate ester synthesis from boron reagents and hydrocarbons
发明人：SMITH III MILTON R
权利人:UNIV MICHIGAN STATE
摘要:A process for producing a ring-substituted arene borane which comprises reacting a ring-substituted arene with an HB organic compound in the presence of a catalytically effective amount of an iridium or rhodium complex with three or more substituents, excluding hydrogen, bonded to the iridium or rhodium and a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium, to form the ring-substituted arene borane. Also provided are catalytic compounds for catalyzing the process comprising an iridium or rhodium complex with three or substituents, excluding hydrogen, bonded to the iridium or rhodium and optionally, a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium.