CAS: 2306-27-6; 2-(3,4-Dimethoxyphenyl)-5,6,7-Trimethoxy-4H-Chromen-4-One

上下游产品

(E)-3-(3,4-dimethoxyphenyl)-1-(6-hydroxy-2,3,4-trimethoxyphenyl)prop-2-en-1-one 3,6-dihydroxy-2,4-dimethoxyacetophenone 3,4-dimethoxybenzoic anhydride 3',4',5,6,7-pentahydroxyflavone3',4',5,6,7-pentahydroxyflavone Veratric acid 1-(2,3,4,6-tetramethoxyphenyl)ethanone 5-desmethylsinensetin

📜3,4,5-三甲氧基苯酚置于三氟化硼乙醚,Potassium Tert-Butylate,碘体系中,用 乙醇,二甲基亚砜 用作溶剂,化学反应 6.5H,反应生成甜橙黄酮
参考文献:大鼠血浆,尿液和粪便中正念珠菌素及其代谢物的生物转化和定量
标题:大鼠血浆,尿液和粪便中正念珠菌素及其代谢物的生物转化和定量
摘要:据报道,作为柑橘皮中主要的多甲氧基黄酮之一,Sinensetin (Sin) 具有多种生物活性.然而,其详细的体内代谢命运尚未被发现.在本研究中,合成了 Sin 的可能代谢物,并通过超高效液相色谱-串联质谱 (Uplc-Ms/ms) 分析在喂食 100 Mg/(Kg.bw) 的大鼠中成功鉴定了所有五种单去甲基化代谢物) 罪.然后进行排泄和药代动力学研究,以定量研究它们在尿液,粪便和血浆样品中的含量随时间的变化.结果表明,4'-去甲基sinensetin,6-Demethylsinensetin和3'-Demethylsinensetin是上述生物样品中产生的三种最丰富的代谢物.此外,尿液中的 Sin 及其代谢物的总量显着高于粪便中的含量,表明 Sin 可能很容易在小肠中被吸收.
Doi:10.1021/acs.Jafc.1C05024

专利信息

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人：NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.