CAS: 2238-90-6; Psychosine

上下游产品

α-galactosyl fluoride (2S,3R,4E)-2-amino-4-°Ctadecene-1,3-diol (2,3,4,6-tetra-O-pivaloyl-α-D-galactopyranoside)-1-trichloroacetimidate (2S,3R,4E)-2-azido-1-(galactopyranosyloxy)°Ctadec-4-en-3-ol(2S,3R,4E)-1-(β-D-galactopyranosyloxy)-2-(°Ctadecanoylamino)-3-hydroxy°Ctadec-4-ene (2S,3R,4E)-1-(β-D-galactopyranosyloxy)-2-(15(Z)-tetracosenoylamino)-3-hydroxy°Ctadec-4-ene (2S,3R,4E)-1-(β-D-galactopyranosyloxy)-2-(hexadecanoylamino)-3-hydroxy°Ctadec-4-ene N-Acetylpsychosine

📜(2S,3R)-(E)-2-Azido-1-(Tert-Butyldiphenylsilyloxy)octadec-4-En-3-Ol置于吡啶,甲醇,4-二甲氨基吡啶,硫化氢,Sodium Methylate,乙酰氯体系中,用 乙醚,二氯甲烷,水 用作溶剂,化学反应 101.92H,反应生成神经鞘氨醇半乳糖苷
参考文献: 3-O-Sulfo-Galactosylceramide Analogs As Activators Of Type Ii Nkt Cells And Uses Thereof[fr] Analogues De 3-O-Sulfo-Galactosylcéramide En Tant Qu'Activateurs De Cellules Nkt De Type Ii Et Leurs Procédés D'Utilisation
标题: 3-O-Sulfo-Galactosylceramide Analogs As Activators Of Type Ii Nkt Cells And Uses Thereof[fr] Analogues De 3-O-Sulfo-Galactosylcéramide En Tant Qu'Activateurs De Cellules Nkt De Type Ii Et Leurs Procédés D'Utilisation
摘要:揭示了一种具有化学式(i)或(II)的化合物:其中a和f如本文所述.这些化合物在激活ii型nkt细胞和治疗癌症方面具有用途.

专利信息

专利号:US-9574189-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries
发明人：FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK
权利人:FRANCH THOMAS; LUNDORF MIKKEL DYBRO; JACOBSEN SØREN NYBOE; OLSEN EVA KAMPMANN; ANDERSEN ANNE LEE; HOLTMANN ANETTE; HANSEN ANDERS HOLM; SØRENSEN ANDERS MALLING; GOLDBECH ANNE; DE LEON DAEN; KALDOR DITTE KIEVSMOSE; SLØK FRANK ABILDGAARD; HUSEMOEN GITTE NYSTRUP; DOLBERG JOHANNES; Jensen Kim Birkebæ; PEDERSEN LENE; NØRREGAARD-MADSEN MADS; GODSKESEN MICHAEL ANDERS; GLAD SANNE SCHRØDER; NEVE SØREN; THISTED THOMAS; KRONBORG TINE TITILOLA AKINLEMINU; SAMS CHRISTIAN KLARNER; FELDING JAKOB; FRESKGÃ…RD PER-OLA; GOULIAEV ALEX HAAHR; PEDERSEN HENRIK; NUEVOLUTION AS
摘要:Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

专利号:US-7429460-B2
优先权日:2003-01-15
标 题 :Methods of screening for inhibitors of phospholipid synthesis related to glycolipid-storage diseases
发明人：FUTERMAN ANTHONY H; BODENNEC JACQUES; PELLED DORI
权利人:YEDA RES & DEV
摘要:The present invention discloses methods of screening for identification of compounds that inhibit novel targets in the enzymatic pathway of phospholipid synthesis that are related to glycolipid storage diseases, and use of the compounds for treating patients affected with glycolipid storage diseases, particularly Gaucher disease. Specifically, the compounds of the present invention are intended to inhibit the accumulation of phosphatidylcholine (PC), wherein PC accumulation is increased due to the activation of CTP:phosphocholine cytidylyltransferase (CCT) upon glucosylceramide (GlcCer) accumulation.

专利号:US-11702652-B2
优先权日:2005-12-01
标题:Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2009264300-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries

专利号:US-2020216836-A1
优先权日:2005-12-01
标题 :Enzymatic encoding methods for efficient synthesis of large libraries