专利号:US-6469133-B2 优先权日:1999-12-13 标题 :Process for the preparation of polymers of dimeric cyclic esters 发明人:BAKER GREGORY L; SMITH III MILTON R 权利人:UNIV MICHIGAN STATE 摘要:The present invention provides a process for the direct synthesis of high melting polymers made from dimeric cyclic esters. In particular, the present invention provides a process for synthesis of polylactic acid (PLA) from racemic materials such as racemic lactide and polymandelide from mandelide. The process further provides racemic metal organic ligand catalysts such as racemic salbinap that catalyzes the polymerization of racemic dimeric cyclic ester monomers to a polylactide stereocomplex. Polymandelide and mixed dimeric cyclic esters are also prepared in the presence of low amounts of water.
专利号:US-9365494-B2 优先权日:2008-12-18 标 题 :Process for synthesis of amino-methyl tetralin derivatives 发明人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN 权利人:DURKIN KIERAN; FISHER LAWRENCE EMERSON; MEILI ARTHUR; SCALONE MICHAELANGELO; SHI XIANQING; VITALE JUSTIN; ROCHE PALO ALTO LLC 摘要:Methods for producing a compound of formula k1 or k2 n nby reducing a dihydronapthalene amide compound of formula in n nwith hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2n nRu(Z) 2 (L)  j1;n nRu(E)(E′)(L)(D)  j2;n nwherein m, n, Ar, Y, R 1 E, E′, D, Z and L are as defined herein.
专利号:WO-2007104357-A1 优先权日:2006-03-14 标 题 :Synthesis of amines with catalytic amounts of mild lewis acids 发明人:NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD 权利人:UNIV JACOBS BREMEN GMBH; NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD 摘要:The invention relates to methods for producing primary, secondary and tertiary amines and corresponding enantiopure or enantioenriched primary or secondary amine products, comprising the steps of reductively aminating a ketone, with a nitrogen auxiliary in the presence of a hydrogenating catalyst and a hydrogenating agent, wherein the reductive animation is performed under the influence of a mild Lewis acid, the mild Lewis acid being present at the onset of the reductive amination in at most 25 mol% of the ketone or the nitrogen auxiliary.
专利号:US-8084641-B2 优先权日:2005-10-11 标 题:Organocataslysts and methods of use in chemical synthesis 发明人:WANG WEI 权利人:WANG WEI; STC UNM 摘要:The present invention is directed to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo-selective reactions, and the method of their synthesis and use.
专利号:US-2013102730-A1 优先权日:2010-04-02 标 题:Polyamine-containing polymers and methods of synthesis and use 发明人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN 权利人:JOST ROBERT W; ULUDAG HASAN; BOLUK MEHMET YAMAN; ALBERTA INNOVATES TECHNOLOGY FUTURES 摘要:The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate).
专利号:US-7220870-B2 优先权日:1995-03-14 标 题:Hydrolytic kinetic resolution of cyclic substrates 发明人:JACOBSEN ERIC N; TOKUNAGA MAKOTO; LARROW JAY F 权利人:HARVARD COLLEGE 摘要:The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.
摘要:Casano, G.; Ouari, O., Science of Synthesis, (2021) , 59. 摘要:Sambiagio, C.; Maes, B. U. W., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 134.