CAS: 16582-93-7; 2,3,4,5-Tetrafluorobenzonitrile

相似化合物

16583-06-5 1201-31-6 773-82-0

上下游产品

CAS号773-82-0 2,3,4,5,6-五氟苯腈 | CAS号551-62-2 1,2,3,4-四氟苯 | CAS号16582-94-8 2,3,4,5-四氟苯甲酰胺 | CAS号16582-94-8 2,3,4,5-四氟苯甲酰胺

2,3,4,5-四氟苯甲酰胺置于phosphorus Pentoxide体系中,化学反应 1.25H,反应生成2,3,4,5-四氟苯甲腈
参考文献:Efremova,N. V.; Starichenko,V. F.; Shteingarts,V. D.,Journal Of Organic Chemistry Ussr (English Translation),1988,Vol. 24,P. 47-56
标题:Efremova,N. V.; Starichenko,V. F.; Shteingarts,V. D.,Journal Of Organic Chemistry Ussr (English Translation),1988,Vol. 24,P. 47-56

专利信息

专利号:US-2009234121-A1
优先权日:2008-01-16
标 题 :Tridentate (nnc) catalysts for the selective oxidation of hydrocarbons
发明人：PERIANA ROY A; GODDARD III WILLIAM A; OXGAARD JONAS; YOUNG KENNETH
权利人:PERIANA ROY A; GODDARD III WILLIAM A; OXGAARD JONAS; YOUNG KENNETH
摘要:The synthesis of discrete, air, protic, and thermally stable transition metal NNC complexes that catalyze the CH activation and functionalization of alkanes and arenes is disclosed. Methods for the selective conversion of methane to methanol or methyl esters in acidic and neutral media are disclosed.

专利号:US-7652178-B2
优先权日:2007-02-26
标题:Perfluoroparacyclophane and methods of synthesis and use thereof
发明人：DOLBIER JR WILLIAM R; XIE PUHUI; KUMAR RAKESH
权利人:SPECIALTY COATING SYSTEMS INC
摘要:A composition comprising perfluoro-[2,2]-paracyclophane dimer compound is disclosed. The synthesis reaction of the paracyclophane dimer from 1,4-bis(chlorodifluoromethane)-2,3,5,6-tetrafluorobenzene involves heating in the presence of a metal catalyst and a solvent. A perfluorinated paraxylylene coating formed from the perfluorinated paracyclophane dimer is also disclosed.

专利号:EP-1641453-B1
优先权日:2003-06-25
标题 :Product containing at least one phosphatase cdc25 inhibitor combined with at least one other anticancer agent
发明人：PREVOST GREGOIRE; BREZAK PANNETIER MARIE-CHRISTINE; DIOLEZ CHRISTIAN
权利人:IPSEN PHARMA
摘要:The invention relates to a product containing at least one phosphatase Cdc25 inhibitor combined with at least one other anticancer agent for simultaneous, separate or staggered therapeutic use during treatment for cancer. According to the invention, the other anticancer agent is preferably selected from: DNA base analogs such as 5-fluorouracil; inhibitors of type I and/or type II topoisomerases, such as camptothecin and the analogs thereof, doxorubicin or amsacrine; compounds interacting with the cellular spindle, for example, paclitaxel (Taxol); compounds acting on the cytoskeleton, such as vinblastine; inhibitors of the transduction of the signal passing via the heterotrimeric G proteins; prenyltransferase inhibitors, and especially farnesyltransferase inhibitors; cyclin-dependent kinase (CDKs) inhibitors; alkylating agents such as cisplatin; folic acid antagonists such as methotrexate; and inhibitors of DNA synthesis and cellular division, such as mitomycin C. The invention also relates to (1R)-1-[({(2R)-2-amino--3-[(8S)-8-(cyclohexylmethyl)-2-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl]--3-oxopropyl}dithio)methyl]-2-[(8S)-8-(cyclohexylmethyl)-2-phenyl--5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl]-2-oxoethylamine, or the pharmaceutically acceptable salts thereof, that can be used as anticancer agents.

专利号:US-2008207961-A1
优先权日:2007-02-26
标 题 :Perfluoroparacyclophane and methods of synthesis and use thereof

专利号:US-9550757-B2
优先权日:2010-03-05
标题:Nuclear transport modulators and uses thereof
发明人：SHACHAM SHARON; KAUFFMAN MICHAEL; SANDANAYAKA VINCENT P; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to the field of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to new substituted-heterocyclic azole compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity such as in treating cancer and other neoplastic disorders, inflammatory diseases, disorders of abnormal tissue growth and fibrosis including cardiomyopathy, pulmonary fibrosis, hepatic fibrosis, glomerulonephritis, and other renal disorders, and for the treatment of viral infections (both acute and chronic).

专利号:WO-2008106286-A2
优先权日:2007-02-26
标题 :Perfluoroparacyclophane and methods of synthesis and use thereof