CAS: 1622-32-8; 2-Chloroethanesulfonyl Chloride

相似化合物

54429-56-0 1633-84-7 594-44-5

上下游产品

CAS号1562-00-1 羟乙基磺酸钠 | CAS号60-24-2 巯基乙醇 | CAS号111-48-8 硫双乙醇 | CAS号75-00-3 氯乙烷 | CAS号107-07-3 2-氯乙醇 | CAS号54509-73-8 ethene | CAS号6301-04-8 S-2-Chloroethyl... | CAS号26650-04-4 chloroethylsulf... | CAS号505-60-2 芥子气 | CAS号928-57-4 2-氯乙基硫代氰酸酯 | CAS号938-09-0 2-氯乙基苯基砜 | CAS号452905-58-7 2,3,4,5,6-五氟-1-... | CAS号21780-04-1 2-Chloroethanes... | CAS号190510-68-0 (2S)-1-ethenyls... | CAS号2039-44-3 β-苯乙烯磺酸钠 | CAS号107-06-2 1,2-二氯乙烷 | CAS号27325-97-9 N-甲基乙烯磺酰胺 | CAS号1562-33-0 (2-chlorophenyl... | CAS号1562-40-9 3-[(2-氯乙基)磺酰基]丙酰胺 | CAS号1562-31-8 Ethenesulfonic ...

硫二甘醇置于盐酸,氯体系中,化学反应生成2-氯乙烷磺酰氯
参考文献:Gladschtein Et Al.,Zhurnal Obshchei Khimii,1958,Vol. 28,P. 2417,2418; Engl.Ausg.S. 2454
标题:Gladschtein Et Al.,Zhurnal Obshchei Khimii,1958,Vol. 28,P. 2417,2418; Engl.Ausg.S. 2454

专利信息

专利号:US-9388147-B2
优先权日:2009-11-13
标题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TIMONY GREGG ALAN; BROOKS JENNIFER L; PEACH ROBERT; SCOTT FIONA LORRAINE; HANSON MICHAEL ALLEN
权利人:RECEPTOS INC; CELGENE INTERNAT II SÃ RL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-2009162290-A1
优先权日:2005-09-09
标 题 :Method for the synthesis of penta-pendant enantiomer-pure chelators and process for therapeutically active bioconjugates preparation by a covalent binding thereof
发明人：BENES IVAN; CIHELNIK SIMON; DROZ LADISLAV; SRAMEK MARTIN
权利人:THERAPHARM GMBH
摘要:The present invention provides a method for synthesis and binding methods of pentapendant enantiomer-pure chelators of formula (VII) wherein R 1 , R 2 , R 3 , R 4 are groups forming an adequate enantiomer of the chelator; and X 1 -X 5 , Y 1 -Y 5 , Z 1 -Z 5 each individually forming pendant chelating groups.

专利号:US-9394264-B2
优先权日:2009-11-13
标 题:Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA
权利人:RECEPTOS INC
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-2025205158-A1
优先权日:2023-12-26
标 题 :Biodegradable lipids and formulations for delivery of mrna
发明人：ANDERSON DANIEL GRIFFITH; RUDRA ARNAB; GUPTA AKASH; REED KAELAN
权利人:MASSACHUSETTS INST TECHNOLOGY; CHILDRENS MEDICAL CENTER
摘要:Provided herein are compounds, such as compounds of Formulae (I), (I′), (XI), (XII), and (XIII), and pharmaceutically acceptable salts, solvates, tautomers, stereoisomers, and isotopically labeled derivatives thereof, and compositions, methods, uses, and kits thereof. The compounds provided herein are lipids useful for delivery of agents, including polynucleotides such as mRNA, for the treatment and/or prevention of various diseases and conditions (e.g., genetic diseases, proliferative diseases, hematological diseases, neurological diseases, liver diseases, spleen diseases, lung diseases, painful conditions, psychiatric disorders, musculoskeletal diseases, metabolic disorders, inflammatory diseases, and autoimmune diseases). Also provided herein are methods of synthesis of compounds of Formulae (I′), (XI), (XII), (XIII), and (VIII).

专利号:US-6403800-B1
优先权日:1998-02-11
标题 :Synthesis of 1-(2-sulfoethyl)-pyridinium betaine
发明人：KAPPES ELISABETH; BRODT GREGOR; KROENER RUDI; WAGNER NORBERT; HILDEBRANDT SOEREN; BOGENSTAETTER THOMAS
权利人:BASF AG
摘要:Described is a process for preparing 1-(2-sulfoethyl)pyridinium betaine wherein pyridine is reacted with a sulfoethylating agent from the group consisting of carbyl sulfate, ethionic acid and its salt and vinylsulfonic acid and vinylsulfonate, the reaction taking place in aqueous solution or in pyridine.

专利号:US-2010204463-A1
优先权日:2007-08-07
标题 :Preparation Of Synthetic Nucleosides via Pi-Allyl Transition Metal Complex Formation
发明人：LIOTTA DENNIS C; LI YONGFENG
权利人:LIOTTA DENNIS C; LI YONGFENG
摘要:This invention provides highly regioselective and stereoselective processes for preparing synthetic nucleosides. A process for the preparation of synthetic nucleosides is provided that comprises a) preparing a bicycloamide derivative, b) reacting the bicycloamide derivative with a nucleic acid base or heterocyclic base or salt thereof in the presence of a transition metal catalyst to form a cyclopentenecarboxamide, and c) cleaving a carboxamide group from the cyclopentenecarboxamide to form the synthetic nucleoside. The processes according to the invention can be used for the synthesis of a variety of anti-viral agents, including Abacavir, Carbovir, and Entecavir, as well as derivatives thereof.