CAS: 14331-56-7; 4-Hydrazinyl-2,6-Dimethylpyrimidine

相似化合物

461-98-3 33592-43-7 54759-99-8

上下游产品

4-chloro-2,6-dimethylpyrimidine 1-(4-Chloro-phenyl)-ethanone O-(2,6-dimethyl-pyrimidin-4-yl)-oxime

📜2-氨基-4-氯-6-甲基嘧啶置于一水合肼体系中,化学反应生成4-肼-2,6-二甲基嘧啶
参考文献:Claesen; Vanderhaeghe,Bulletin Des Societes Chimiques Belges,1959,Vol. 68,P. 30,55
标题:Claesen; Vanderhaeghe,Bulletin Des Societes Chimiques Belges,1959,Vol. 68,P. 30,55

专利信息

专利号:US-9714226-B2
优先权日:2011-07-29
标题:Hydrazide containing nuclear transport modulators and uses thereof
发明人：SANDANAYAKA VINCENT P; SHACHAM SHARON; MCCAULEY DILARA; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to a compound represented by structural formula I: n nor a pharmaceutically acceptable salt thereof, wherein the values and alternative values for the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of structural formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity.