CAS: 141567-53-5; (2-Methyloxazol-4-yl)Methanol
该化合物是一种多用途的七环醇,分子式为C5H7NO2,其氧化氮核心在4级被氢氧化硫组和2级被2级组替代,使其成为有机合成和制药应用中有价值的中间体.该化合物具有进一步功能化的良好反应性,能够用于制造更复杂的循环系统或生物活性分子.在标准条件下保持稳定,与共同合成方法相容,增强了其在研究和工业环境中的效用.该氢氧化氮组为衍生提供了方便的处理器,促进了医药化学和材料科学的应用.
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- 产品信息参考
- InChIKey: BGPDSEDYUPFTBI-UHFFFAOYSA-N
- InChI=1S/C5H7NO2/c1-4-6-5(2-7)3-8-4/h3,7H,2H2,1H3
- 计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数1.0
相似化合物
113732-84-6 85806-67-3 10200-43-8物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号85806-67-3 2-甲基噁唑-4-甲酸甲酯 | CAS号10200-43-8 2-甲基-4-噁唑甲酸乙酯 | CAS号23012-17-1 2-甲基恶唑-4-羧酸 | CAS号110-71-4 乙二醇二甲醚 | CAS号1191-15-7 二异丁基氢化铝 | CAS号141029-63-2 4-Oxazolecarbox... | CAS号155884-28-9 4,5-二氢-2-甲基-1,3... | CAS号875553-59-6 2-甲基噁唑-4-羧酸 N-甲... | CAS号147438-64-0 4-(3-diphenylph... | CAS号134332-63-1 5-ethyl-2-metho... | CAS号657389-99-6 4-溴甲基-2-甲基噁唑 | CAS号552849-98-6 4-(dimethoxypho...合成工艺路线路线简述
📜2-甲基恶唑-4-羧酸置于二异丁基氢化铝体系中,用 正己烷,二氯甲烷 用作溶剂,化学反应 3.0H,以60%的收率获得2-甲基-4-恶唑甲醇
参考文献:Total Synthesis Of Oxazole-Based Virginiamycin Antibiotics: 14,15-Anhydropristinamycin Iib
标题:Total Synthesis Of Oxazole-Based Virginiamycin Antibiotics: 14,15-Anhydropristinamycin Iib
摘要:
Doi:10.1055/s-1998-5935
海关参考信息
- 2905110000-甲醇
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2021238187-A1
优先权日:2017-04-11
标 题:Aziridine containing epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates
发明人：NICOLAOU KYRIACOS C; RHOADES DEREK; WANG YANGPING
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present disclosure provides epothilone analogs of the formula: (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided.
专利号:WO-2018191394-A1
优先权日:2017-04-11
标题 :Aziridine containing epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates
专利号:EP-3609538-A1
优先权日:2017-04-11
标题 :Aziridine containing epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates
专利号:CA-3059885-A1
优先权日:2017-04-11
标 题:Aziridine containing epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates
专利号:CN-110944664-A
优先权日:2017-04-11
标题:Aziridines containing epothilone analogs, methods of synthesis, methods of treatment, and drug conjugates
专利号:RU-2059636-C1
优先权日:1990-07-19
标题:Oxazolyl-derivatives or their pharmaceutically acceptable additive salt, or their stereochemically isomeric form, a method of their synthesis and pharmaceutical composition showing antiallergic activity
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📌 第三方产品分析报告
合成参考文献
参考文献:10.1055/s-2007-982556
摘要:Yadav J, Satyanarayana M, Srinivasulu G, Kunwar A. A Stereoselective Synthesis of the C20-C32 Fragment of the Phorboxazoles. Synlett. 2007 Jun;2007(10):1577–80. doi: 10.1055/s-2007-982556.
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