CAS: 124495-18-7; Quinoxyfen

该化合物是一种合成化学化合物,主要用作农业应用中的杀真菌剂,特别是用于控制各种作物中的粉末,属于quinoline衍生物类别,并展示了一种独特的行动方式,扰乱真菌细胞的分化.昆克西芬的特点是对非目标生物的毒性相对较低,使其在综合虫害管理系统中成为首选选择.该化合物通常作为一种花生喷雾施用,因其系统特性而闻名,允许植物吸收它,并针对真菌病原体提供扩大保护.其功效受温度和湿度等环境因素的影响,这些因素可能影响其稳定性和性能.此外,昆克西芬有特定的化学结构,有助于其生物活动,并须接受监管评估,以确保安全和环境影响.总的来说,昆克西芬是现代农业管理真菌疾病和尽量减少对有益生物的危害的重要工具.

结构式图片

相似化合物

124495-31-4 1094937-81-1 879324-21-7

欧盟法规

[REACH注册ECHA物质ECHA物质C&L通报REACH预注册

合成工艺路线路线简述

  • 合成目标产物 Quinoxyfen 主要起始原料 4,5,7-Trichloro Quinoline And Sodium 4-Hydroxyphenolate
  • (文献来源)合成步骤主要原料 4,5,7-Trichloro Quinoline 和 Sodium 4-Hydroxyphenolate
📜Ethyl 3,5-Dichloroanilinopropionate置于palladium On Activated Charcoal,Sodium Hydroxide,三氯氧磷体系中,用 乙醇,水,1,2-二氯乙烷,N,N-二甲基甲酰胺,甲苯 用作溶剂,化学反应 23.0H,反应生成喹氧灵
参考文献:一种苯氧喹啉及其合成方法
标题:一种苯氧喹啉及其合成方法
摘要:本发明公开了一种苯氧喹啉及其合成方法,该苯氧喹啉包括以下原料:水,丙烯酸乙酯,氯化锌,冰醋酸,3,5‑二氯苯胺,乙醇,氢氧化钠,甲苯,多聚磷酸,正辛烷,Pd/c催化剂,二氯乙烷,三氯氧磷,对氟苯酚和n,N‑二甲基甲酰胺.本发明所得的苯氧喹啉的含量大于98.0%,收率为50%以上,生产成本低,其合成苯氧喹啉过程中不需要经过水解,高温脱羧等工艺,操作步骤少,反应条件温和,设备要求低,生产的产品质量较好,适用于企业规模化生产.

海关参考信息

专利信息


专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-2016073631-A1
优先权日:2013-03-04
标 题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-9233920-B2
优先权日:2010-06-11
标题 :Process for the preparation of dihydropyrrole derivatives
发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS
权利人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS; SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD
摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R 1 is chlorodifluoromethyl or trifluoromethyl; R 2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R 1 and R 2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R 1 and R 2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

专利号:US-10906880-B2
优先权日:2016-01-26
标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
权利人:UNIV NANKAI
摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

专利号:US-9968097-B2
优先权日:2012-05-30
标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
权利人:BAYER CROPSCIENCE AG
摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

专利号:US-2007232495-A1
优先权日:2006-03-24
标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

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✅ COA系统入驻 | 共享模式

主要参考文献


1: Duman B, Erkmen C, Zahirul Kabir M, Ching Yi L, Mohamad SB, Uslu B. In vitro interactions of two pesticides, propazine and quinoxyfen with bovine serum albumin: Spectrofluorometric and molecular docking investigations. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Nov 5;300:122907. doi: 10.1016/j.saa.2023.122907. Epub 2023 May 25. 27(12):3946. doi: 10.3390/molecules27123946.
3: Tait S, Lori G, Tassinari R, La Rocca C, Maranghi F. In Vitro Assessment and Toxicological Prioritization of Pesticide Mixtures at Concentrations Derived from Real Exposure in Occupational Scenarios. Int J Environ Res Public Health. 2022 Apr 25;19(9):5202. doi: 10.3390/ijerph19095202.
4: Birtek RI, Karpuzcu ME, Ozturk I. Occurrence of priority substances in urban wastewaters of Istanbul and the estimation of the associated risks in the effluents. Environ Monit Assess. 2022 May 13;194(6):426. doi: 10.1007/s10661-022-09840-w. 129(7):77006. doi: 10.1289/EHP6886. Epub 2021 Jul 29.

合成参考文献


摘要:Galczynski, J.; Huang, H.; Lambert, T. H., Science of Synthesis: Special Topics, (2021) 1, 338.
摘要:WHO (2010) The WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2009, International Programme on Chemical Safety, p.45
摘要:US EPA; Reregistration Review: Summary of Planned Schedule for Opening Registration Review Dockets by Fiscal Year 2011 to 2014. April 1, 2011. Washington, DC; USEPA, Off Pest Prog. Available from, as of June 23, 2011:
摘要:Meister, R.T., Sine, C; Crop Protection Handbook Volume 94. Meister Media Worldwide, Willoughby, OH 2008, p. D 383
摘要:Lyman WJ et al; Handbook of Chemical Property Estimation Methods. Washington, DC: Amer Chem Soc pp. 7-4, 7-5, 8-12 (1990)
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