CAS: 78617-12-6; (2R,3R,4S,5S,6R)-2-(Heptyloxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是生物化学和生物物理研究中广泛使用的一种非电离烷基甘油表面活性剂,其主要优点包括纯度高,稳定性强和清洁剂温和,适合不衰减地溶解膜蛋白.七基链长为疏水性和水利生殖性之间提供了最佳平衡,有利于高效提取蛋白,同时保持本地兼容性.这种化合物在结晶研究和结构生物学中特别宝贵,因为它能够形成定义明确的小鼠.此外,它显示出低临界临界小鼠浓度,提高了实验应用的有效性.它与广泛的pH值范围的兼容性和抗酶降解的抗力进一步突出了其在实验室环境中的效用.

结构式图片

上下游产品

CAS号28245-00-3 n-heptyl 2,3,4,... | CAS号111-70-6 正庚醇 | CAS号57-50-1 蔗糖 | CAS号572-09-8 2,3,4,6-四乙酰氧基-a... | CAS号604-69-3 β-D-葡萄糖五乙酸酯 | CAS号2492-87-7 4-硝基苯基-β-D-吡喃葡萄糖苷 | CAS号69984-73-2 壬基-Β-D-葡萄吡喃糖甙 | CAS号5391-18-4 丁基葡糖苷 | CAS号25320-96-1 1-pentanol β-D-... | CAS号492-61-5 β-D-葡萄糖 | CAS号111-70-6 正庚醇 | CAS号58846-77-8 癸基 Β-D-吡喃葡萄糖苷 | CAS号69984-73-2 壬基-Β-D-葡萄吡喃糖甙

合成工艺路线路线简述

    📜戊基beta-D-吡喃葡萄糖苷置于水体系中,用 水 作为反应溶剂,化学反应 168.0H,反应生成 庚基-β-D-吡喃葡萄糖苷
    参考文献:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst
    标题:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst
    摘要:An Array Of Ten Beta-D-Glueopyranosides With Varied Alkyl Chain Lengths Were Enzymatically Synthesized. It Was Found That For Longer Alkyl Chains A Lower Initial Rate And Final Yield Of Glucoside Was Obtained Except For Methyl Glucoside Because Of The Severe Toxicity Of Methanol To The Enzyme. From A Thermodynamics Point Of View,The Equilibrium Constant And Gibbs Free Energy Variation Of The Glucoside Syntheses Were Systematically Investigated. To Improve The Final Yields Of The Glucosides Containing Long Alkyl Chains The Equilibrium Of The Enzymatic Glucoside Synthesis Was Altered. The Equilibrium Yield Of Decyl Beta-D-Glucoside Increased From 1.9% To 6.1% When The Water Content Was Reduced From 10% To 5% (V/v) Using Tert-Butanol As A Cosolvent And 0.10 Mol/l Of Glucose As A Substrate. As For The Other Longer Alkyl Chain Glucosides,Heptyl Beta-D-Glucoside Was Found To Have Significant Surface Activity As Well.
    DOI:10.1016/s1872-2067(11)60333-1

    海关参考信息

    专利信息


    专利号:US-2006211083-A1
    优先权日:2005-01-21
    标题:Products and processes for in vitro synthesis of biomolecules
    发明人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
    权利人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
    摘要:Provided herein are products and processes for efficiently synthesizing biomolecules in vitro using cell-free extracts derived from mammalian cells and insect cells. In an embodiment, provided is a process for preparing a cell-free extract from insect cells and mammalian cells that efficiently synthesizes post-translationally modified target proteins (e.g., glycosylated target proteins). In some embodiments, a ribonucleic acid is synthesized in vitro that comprises a cap, a 5′ untranslated region comprising an 18S rRNA binding ribonucleotide sequence, and a target ribonucleotide sequence. It has been determined that such ribonucleic acids result in efficient in vitro synthesis of a target protein using cell-free extracts derived from non-rabbit mammalian cells and insect cells.

    专利号:US-2001049117-A1
    优先权日:1998-08-20
    标 题 :Analogs of udp-murnac peptides, assays, kits and related methods of their use
    发明人:AXELROD HELENA R; BRANSTROM ARTHUR A
    摘要:General compositions and methods for detecting Lipid I, Lipid II and peptidoglycan synthesis is disclosed. A method of screening for potential antibacterial agents is provided which requires bacterial membrane preparations or enriched enzyme preparations including at least one bacterial enzyme involved in the synthesis of Lipid I from UDP-MurNAc pentapeptide and undecaprenyl phosphate, at least one bacterial enzyme involved in the synthesis of Lipid II from Lipid I and UDP-GlcNAc and one or more bacterial enzymes involved in the further processing of Lipid II toward the downstream synthesis of peptidoglycan. The methods disclosed herein further provides a labeled UDP-MurNAc-peptide capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid I and a labeled UDP-GlcNAc capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid II. Conditions for further processing of Lipid II toward the downstream synthesis of peptidoglycan are also discribed.

    专利号:WO-2006078821-A2
    优先权日:2005-01-21
    标题:Products and processes for in vitro synthesis of biomolecules

    专利号:US-2010055187-A1
    优先权日:2008-08-28
    标题:Nanovitamin synthesis
    发明人:AHN DONG JUNE
    权利人:AHN DONG JUNE
    摘要:Stable nanoparticulate vitamin compositions are prepared from agglomerated or larger sized vitamin particles of at least one vitamin compound by breaking down and/or solubilizing the agglomerated or larger sized vitamin particles and associating the particles with a surface modifying agent.

    专利号:US-2009028948-A1
    优先权日:2004-12-31
    标 题 :Nanoparticle composition and methods of synthesis thereof

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:S55 | ZINC15PHARMA | Pharmaceuticals from ZINC15 | DOI:10.5281/zenodo.3247749
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知