CAS: 613-89-8; 2-Amino-1-Phenyl-Ethanone

该化合物是一种多用途有机化合物,其特点是一个联苯集团,与氨基替代乙酮框架结合,这一结构使其成为合成有机化学中有价值的中间体,特别是在制药,农用化学品和精细化学品的准备方面.它的活性氨基和碳基组允许多种功能化,有利于在热循环合成和手动衍生中应用.该化合物在受控条件下的稳定性和与各种反应条件的兼容性增强了其在多步骤合成中的效用.由于它具有潜在的敏感性,需要适当处理.它通常用于研究和工业环境中开发生物活性分子和特殊材料.

结构式图片

上下游产品

CAS号100-97-0 乌洛托品 | CAS号70-11-1 2-溴苯乙酮 | CAS号1816-88-2 2-azido-1-pheny... | CAS号93-97-0 苯甲酸酐 | CAS号532-54-7 2-异亚硝基苯乙酮 | CAS号38061-18-6 5-苯基噁唑-4-甲酸甲酯 | CAS号98-88-4 苯甲酰氯 | CAS号28541-43-7 (E)-1,1-dimethy... | CAS号74-88-4 碘甲烷 | CAS号613-90-1 苯甲酰腈 | CAS号5468-37-1 2-氨基苯乙酮盐酸盐 | CAS号143707-88-4 5-ethyl-6-methy... | CAS号3176-62-3 3-甲基-1H-吲唑 | CAS号830-74-0 1-烯丙基靛红 | CAS号6857-34-7 4-苯基咪唑-2-硫醇 | CAS号7568-93-6 2-氨基-1-苯基乙醇 | CAS号74718-16-4 5-苯基-2-(4-吡啶)噁唑 | CAS号529-37-3 喹啉-4(1H)-酮 | CAS号13337-77-4 N-phenacylpyrid... | CAS号102542-89-2 5-phenyl-2-(2-p...

合成工艺路线路线简述

  • 合成目标产物 2-Aminoecetophenone 主要起始原料 2-Bromoacetophenone
  • (文献来源)合成步骤主要原料 2-Bromoacetophenone
📜苯甲酰硝基甲烷置于氢气体系中,60.0 °C,5.0 Mpa 条件下,反应 4.0H,反应生成 2-氨基苯乙酮
参考文献:Efficient Palladium And Ruthenium Nanocatalysts Stabilized By Phosphine Functionalized Ionic Liquid For Selective Hydrogenation
标题:Efficient Palladium And Ruthenium Nanocatalysts Stabilized By Phosphine Functionalized Ionic Liquid For Selective Hydrogenation
摘要:钯和钌纳米颗粒由新型膦功能化离子液体稳定,最初被用作优秀的化学选择性加氢催化剂.
DOI:10.1039/c5Ra01893E

海关参考信息

专利信息


专利号:US-2023339844-A1
优先权日:2020-09-17
标题:A process for the synthesis of anthranilic acid/amide compounds and intermediates thereof
发明人:MAHAPATRA TRIDIB; PATRA PRANAB KUMAR; KLAUSENER ALEXANDER G M; MAL SANJIB; SHARMA RAJU
权利人:PI INDUSTRIES LTD; PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of compound of formula (Z) or a salt thereof, n n n n n n n n n n wherein, R, R 1 , R 2 , R 3 and R 10 are as defined in the detailed description. The process further comprises the synthesis of an anthranilic diamide compound of formula (I).

专利号:US-2023348492-A1
优先权日:2020-05-04
标题:Photochemical synthesis of marmycin analogues through a new photochemical reaction involving carbonyl compounds
发明人:SIVAGURU JAYARAMAN; KANDAPPA SUNIL KUMAR; VALLOLI LAKSHMY KANNADI
权利人:BOWLING GREEN STATE UNIV
摘要:Photochemical reactivity of carbonyl compounds leading to the synthesis of the Marmycin core is described. The photochemical reactivity involves an excited state reaction that provides convenient access to bicyclic compounds. The disclosed reactivity is a new photochemical pathway involving 1,3-dicarbonyl compounds and amines as well as for enaminones.

专利号:US-4879389-A
优先权日:1986-06-25
标题:Chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds
发明人:ACHIWA KAZUO
权利人:ACHIWA KAZUO
摘要:New chiral phosphinopyrrolidine compounds of the general formula: (I) or (I') wherein R1 is a hydrogen atom, -COR, -COOR, -CONHR or -SO2-R where R is an alkyl or aryl group, R2 and R3 each represents independently an aryl group which may have a substituent or substituents, and R4 and R5 each represents independently an aliphatic or cycloaliphatic hydrocarbyl group which may have a substituent or substituents, as well as the use of these compounds as ligand for a metal complex catalyst for asymmetric synthesis of optically active compounds. The new chiral phosphinopyrrolidine compounds are useful ligands which attain both of high optical yield and high reaction efficiency in catalytic asymmetric reduction.

专利号:EP-1383732-B1
优先权日:2001-05-04
标题:Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules
发明人:BOURGET CECILE; LHOMME JEAN; LAAYOUN ALI; KOTERA MITSUHARU; TREVISIOL EMMANUELLE; MENOU LIONEL; BERNAL MENDEZ ELOY
权利人:BIO MERIEUX; UNIV GRENOBLE 1; CENTRE NAT RECH SCIENT
摘要:The invention concerns a temperature-stable labelling reagent of formula (I), wherein: R<1> represents H or an alkyl, aryl or substituted aryl group; R<2> represents a detectable marker or at least two detectable markers linked together by at least a multimeric structure; L is a linking arm comprising a linear catemer concatenation of at least two covalent bonds; and n is an integer equal to 0 or 1; R<3> and R<4> represent, independently of each other: H, NO2, Cl, Br, F, I, R<2>-(L)n-Y-X-, OR, SR, NR2, R, NHCOR, CONHR, COOR with R = alkyl or aryl, A is a linking arm comprising at least a double bond enabling the conjugation of the diazo function with the aromatic cycle; and u is a whole number between 0 and 2, preferably between 0 and 1; and -Y-X- represents -CONH-, -NHCO-, -CH2O-, -CH2S-. The invention also concerns a method for the synthesis of said markers and uses for labelling biological molecules, in particular nucleic acids, with a labelling reagent bearing the diazomethyl function. The invention is particularly applicable in the field of diagnosis.

专利号:US-9150497-B2
优先权日:2011-10-14
标题 :Continuous two step flow synthesis of M-amino acetophenone
发明人:KULKARNI AMOL ARVIND; JOSHI RAMESH ANNA; JOSHI ROHINI RAMESH
权利人:COUNCIL SCIENT IND RES
摘要:Disclosed herein is a continuous tubular reactor based conversion of acetophenones to amino substituted acetophenones wherein the nitration is carried out at −10 to 10° C. followed by reduction to m-nitrophenone resulting in uniform output of product, said process comprising the steps of: a) Nitrating acetophenone with nitrating agent (nitration mixture or fuming nitric acid) at −10 to 10° C.; b) Isolating m-nitro acetophenone from a mixture of o and m-nitro acetophenone and c) Reducing the m-nitro to obtain m-amino acetophenone.

专利号:US-4894456-A
优先权日:1987-03-31
标题 :Synthesis of camptothecin and analogs thereof
发明人:WALL MONROE E; WANI MANSUKH C; NICHOLAS ALLAN W; MANIKUMAR GOVINDARAJAN
权利人:RES TRIANGLE INST
摘要:A method for synthesizing camptothecin and camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase I and show anti-leukemic and anti-tumor activity.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Osuna Gálvez, A.; Bode, J. W., Science of Synthesis Knowledge Updates, (2020) 1, 386.
摘要:Llopis, Q.; Ayad, T.; Phansavath, P.; Ratovelomanana-Vidal, V., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 109.
摘要:NOMINE G, PENASSE L, DELAROFF V. [The penicillinate of 2,5-diphenylpiperazine; retardedaction form of penicillin. II. Alkaline cyclization of phenacylamine]. Ann Pharm Fr. 1958 Jun;16(6):436–41.
参考文献:10.1107/s1600536810027650
摘要:Khan FN, Roopan SM, Malathi N, Hathwar VR, Akkurt M. N-[2-(4-Methyl-2-quinolyl)phenyl]acetamide: aP1 structure withZ= 4. Acta Crystallogr E Struct Rep Online. 2010 Jul 17;66(8):o2043–4. doi: 10.1107/s1600536810027650.
参考文献:10.1007/978-1-4939-2854-5_10
摘要:Liebens V, Defraine V, Fauvart M. A Whole-Cell-Based High-Throughput Screening Method to Identify Molecules Targeting Pseudomonas aeruginosa Persister Cells. Methods Mol Biol. 2016;1333():113–20. doi: 10.1007/978-1-4939-2854-5_10.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知