CAS: 548-39-0; Perinaphthenone

相似化合物

7465-58-9 203-80-5 196953-12-5

上下游产品

phenalene H-phenalene-1,9-dicarboxylic acid4-oxo-4H-phenalene-1,9-dicarboxylic acid H-phenalene-2-carboxylic acid1-oxo-1H-phenalene-2-carboxylic acid (Z)-3-(naphthalen-1-yl)acrylic acidDibenzo[c,mno]chrysene 9-phenyl-1H-phenalene-1-one phenalene peropyrene

4-Oxo-4H-Phenalene-1,9-Dicarboxylic Acid置于extinguished Lime,Calcium Carbonate体系中,化学反应生成 萘嵌苯酮
参考文献:Bamberger; Philip,Justus Liebigs Annalen Der Chemie,1887,Vol. 240,P. 185
标题:Bamberger; Philip,Justus Liebigs Annalen Der Chemie,1887,Vol. 240,P. 185

专利信息

专利号:WO-2024002966-A1
优先权日:2022-06-29
标题 :Hydrophilic phenalenones and their use in antimicrobial photodynamic therapy
发明人：COEFFARD VINCENT; DE BONFILS PAUL; NUN PIERRICK; ZITOUNI BÉCHIR; SOL VINCENT; VERNISSE CHARLOTTE; OUK TAN-SOTHEA; GUNTHER GERMAN
权利人:CENTRE NAT RECH SCIENT; UNIV NANTES; UNIV OF CHILE; UNIV LIMOGES
摘要:The present invention belongs to the field of antimicrobial compositions and antimicrobial photodynamic therapy, and more specifically to hydrophilic phenalenones and their use in said field. It relates more specifically to new yellow-fluorescent phenalenone photosensitizers for applications in antimicrobial photodynamic therapy (aPDT). The present invention relates to new hydrophilic phenalenones compounds and their use as a medicine, in antimicrobial photodynamic therapy, and more specifically in the treatment of various diseases, such as acne vulgaris, periodontis infections, rosacea, ptyriasis versicolor, molluscum contagiosum, genital herpes, tinea pedis, endodontics infections, viral keratitis, COVID-19 or influenza. The invention also relates to the method of synthesis of new hydrophilic phenalenone compounds according to the invention.

专利号:US-9670217-B2
优先权日:2008-10-24
标题 :Process for preparing chlorins and their pharmaceutical uses
发明人：DA SILVA ARNAUT MOREIRA LUIS GUILHERME; PEREIRA MARIA MIGUÉNS; Formosinho SanchesSimõs Sebastião José; MAGALHÃES SIMÕES Sérgio Paulo; STOCHEL GRAZYNA; URBANSKA KRYSTYNA
权利人:DA SILVA ARNAUT MOREIRA LUIS GUILHERME; PEREIRA MARIA MIGUÉNS; Formosinho SanchesSimõs Sebastião José; MAGALHÃES SIMÕES Sérgio Paulo; STOCHEL GRAZYNA; URBANSKA KRYSTYNA; UNIV DE COIMBRA
摘要:The disclosed subject matter includes methods of preparation, properties, pharmaceutical compositions and methods of therapy of sulfonated chlorins and bacteriochlorins designed for the photodynamic therapy (PDT) of hyperproliferative tissues such as tumors, hyperproliferative blood vessels and other disorders or abnormalies that are responsive to PDT. In particular, the economical large-scale synthesis of stable chlorins and bacteriochlorins is described. Their properties were tailored to meet those of ideal photosensitizers for PDT. In another embodiment, pharmaceutical compositions and methods of therapy for systemic administration are provided. In a further embodiment, pharmaceutical compositions and methods of therapy for topical administration are also provided. Further provided is a method of labeling a target tissue and providing an image of that tissue by fluorescence of magnetic resonance imaging.

专利号:US-10138510-B2
优先权日:2008-05-16
标题 :Dual labeling methods for measuring cellular proliferation
发明人：CLARKE SCOTT; BRADFORD JOLENE
权利人:LIFE TECHNOLOGIES CORP
摘要:The present invention provides a method for measuring cellular nascent nucleic acid synthesis by dual pulse labeling of nucleic acid. The first pulse labeling of nucleic acid with a nucleoside analog allows establishment of a baseline nucleic acid synthesis rate. Pulse labeling of the nucleic acid with a second nucleoside analog then allows measurement of any changes to nucleic acid synthesis. The nucleic acid synthesis can be measured as cell proliferation, DNA, or gene expression, RNA. This method does not require a potentially artifact-inducing intermediary wash step between pulse labels. Additionally, this method may be used to screen compounds for their affect on cellular proliferation by treating cells or an organism with the test compound simultaneous to or before treatment with a competitive nucleoside analog.

专利号:US-2019154696-A1
优先权日:2015-08-31
标 题 :Colorimetric Labeling and Detection Methods and Compositions
发明人：CLARKE SCOTT; GEE KYLE; FINNESSY CARMEN
权利人:LIFE TECHNOLOGIES CORP
摘要:The present disclosure provides methods, compositions and kits for measuring cellular nascent nucleic acid synthesis by colorimetric labeling of nucleic acid. The nucleic acid synthesis can be measured as cell proliferation, DNA or RNA synthesis, gene expression or apoptosis. Additionally, these methods may be used to screen compounds for their effect on cellular proliferation by treating cells or an organism with the test compound simultaneous to or before treatment with a competitive nucleoside analog.

专利号:US-8513451-B2
优先权日:2007-05-30
标 题:Fluorescent phospholipase A2 indicators
发明人：KANG HEE CHOL
权利人:KANG HEE CHOL
摘要:Compositions, methods of synthesis and applications of phospholipase A 2 (PLA 2 ) specific enzyme substrates which exhibit fluorescence resonance energy transfer (FRET) are described. The compounds generally have the structure: (I) wherein, the variables are described throughout the application. These novel compounds provide a sensitive method to monitor real time PLA 2 specific enzyme activities in various cells, tissues and small organisms with fluorescence-ratiometric analysis.

专利号:US-9341631-B2
优先权日:2007-06-05
标题 :Long wavelength fluorogenic intracellular ion indicators that are well retained in the cytosol
发明人：GEE KYLE; MARTIN VLADIMIR
权利人:GEE KYLE; MARTIN VLADIMIR; LIFE TECHNOLOGIES CORP
摘要:Cell permeable metal ion indicator compounds and methods of their use and synthesis are described. The compound comprises a metal chelating moiety (M c ), a reporter molecule and two or more lipophilic groups (G L ) covalently bonded through a linker to the reporter molecule, wherein the lipophilic groups, when present in a live cell, are cleaved resulting in two or more negatively charged groups. An exemplary compound for use as a cell permeable metal ion indicator is represented by the structure: