CAS: 20316-62-5; ((2R,3S,4S,5R,6S)-6-((5,7-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4H-Chromen-3-yl)Oxy)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-yl)Methyl (E)-3-(4-Hydroxyphenyl)Acrylate

该化合物是多种植物,特别是Tilia genus(树苗)和其他药用草药中发现的浮质甘油,其特点是结构结构,由一种与甘蔗糖(通常是甘蔗糖)相连的浮质甘油组成. 硅酸盐展示了多种生物活动,包括抗氧化剂,抗炎剂和潜在的保护性心血管效应,因此对药理研究感兴趣.它的抗氧化性特性可归因于其可导致细胞损伤和各种疾病的碳酸自由基.此外,还研究了硅酸盐在改变代谢过程方面的潜在作用及其对心血管健康的影响.该化合物一般被认为是安全的,但其生物利用率和功效可能因提取来源和方法而不同.随着研究的继续,化肥可能会提供对天然治疗剂及其在健康和健康方面的应用的洞察.

结构式图片

上下游产品

trans-tiliroside 6''-O-p-coumaroylastragalin heptaacetate kaempferol 3-O-(3'',6''-di-O-E-p-coumaroyl)-β-D-glucopyranoside Tilirosidetrans-tiliroside astragalin p-Coumaric Acid D-Glucose

合成工艺路线路线简述

    📜Kaempferol 3-O-(6''-E-P-Coumaroyl-β-D-Glucopyranoside)-7-O-β-D-Glucopyranoside置于acetate Buffer,β-Glucosidase体系中,化学反应 24.0H,反应生成银锻苷
    参考文献:莲藕酰化黄酮醇二糖苷
    标题:莲藕酰化黄酮醇二糖苷
    摘要:三酰化黄酮醇二糖苷,山奈酚 3-O-β-(6"-Oep-香豆酰葡萄糖苷)-7-O-β-葡萄糖苷;槲皮素 3-O-β-(6"-Oep-香豆酰葡萄糖苷)-7-O-β-葡萄糖苷;异鼠李素 3-O-β-(6"-Oep-香豆酰葡萄糖苷)-7-O-β-葡萄糖苷是从莲藕的全植物水醇提取物中分离出来的.已知的苷元的 3,7-Di-O-葡萄糖苷还表征了山奈酚,槲皮素和异鼠李素.所有结构均建立在化学和光谱证据的基础上.
    Doi:10.1016/s0031-9422(02)00177-2

    专利信息


    专利号:EP-1493431-B1
    优先权日:2003-07-03
    标题:Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions
    发明人:WIRTH CORINNA DR; BUCHHOLZ HERWIG DR
    权利人:MERCK PATENT GMBH
    摘要:Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for cosmetic or pharmaceutical treatment of skin and hair. Use of an aqueous or aqueous-alcoholic extract (A) of Bauhinia is claimed to make a composition for: (a) care, preservation or improvement of the general condition of the skin or hair; (b) prevention and/or inhibition of the aging process for human skin or hair; (c) for promoting healing of wounds; (d) for prevention and/or treatment of skin diseases associated with abnormal keratinization, and (e) for prevention and/or treatment of all malignant or benign growths of the dermis or epidermis. An independent claim is also included for a composition containing (A). ACTIVITY : Dermatological; Vulnerary; Antiseborrheic; Antipsoriatic; Cytostatic; Antiinflammatory; Virucide. MECHANISM OF ACTION : Protein glycosylation inhibitor. In a test, human fibroblasts were cultured in the presence of Vitamin C to stimulate collagen synthesis, then lysed and labeled with tritiated glucose for 15 days, Proteins were removed, extraction and precipitation were carried and the amount of bound glucose measured by liquid scintillation counting. Addition of an aqueous-alcoholic extract of Bauhinia fortificata (0.03 mg/ml), reduced protein glycosylation to 55% of that in a control.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Bertella A, Smadi A, Benhabrou H, Salvador D, Wrona M, Oliveira H, Sidaoui A, Gavril-Luminita G, Pinto DCGA, Olewnik-Kruszkowska E, Nerín C, Silva AMS, Bitam F. Phytochemical Study and In Vitro Antioxidant Activity of Helianthemum cinereum Along with Antitumor Activity of the Isolated trans-Tiliroside and Luteolin 4'-O-β-Xyloside. Molecules. 2024 Dec 16;29(24):5935. doi: 10.3390/molecules29245935.
    287:138590. doi: 10.1016/j.ijbiomac.2024.138590. Epub ahead of print. 15(11):2220-2236. doi: 10.4239/wjd.v15.i11.2220.
    4: Feng X, Qin Y, Ma S, Ming S, Weng Z, Xuan Y, Gong S, Fan F, Chen P, Chu Q, Li Z. Liubao tea extract restrains obesity-related hyperlipidemia via regulation of AMPK/p38/NF-κB pathway and intestinal microbiota. Food Chem. 2025 Feb 1;464(Pt 3):141910. doi: 10.1016/j.foodchem.2024.141910. Epub 2024 Nov 5.

    合成参考文献


    参考文献:10.1021/np960057s
    摘要:Lale A, Herbert JM, Augereau JM, Billon M, Leconte M, Gleye J. Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes. J Nat Prod. 1996 Mar;59(3):273–6. doi: 10.1021/np960057s.
    参考文献:10.1007/s00394-011-0204-5
    摘要:Tsimplouli C, Demetzos C, Hadzopoulou-Cladaras M, Pantazis P, Dimas K. In vitro activity of dietary flavonol congeners against human cancer cell lines. European Journal of Nutrition. 2011 May 20;51(2):181–90. doi: 10.1007/s00394-011-0204-5.
    参考文献:10.1055/s-2008-1074547
    摘要:Ren ZY, Qi HY, Shi YP. Phytochemical investigation of Anaphalis lactea. Planta Med. 2008 Jun;74(8):859–63. doi: 10.1055/s-2008-1074547.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知