CAS: 198127-92-3; N,N-Dimethyl 4,5-Diiodo-1H-Imidazole-1-Sulfonamide
该化合物是一种化学化合物,其特点是其非碘环形结构,即五人组成的含有氮原子的热循环化合物,在伊米德佐尔环的4和5个位置上存在两个碘原子,造成其独特的特性,包括分子重量增加,并有可能增强再活性; 全氟辛烷磺酸功能组,其中包括一个硫磺原子,与一个磺酰基组(EurosO2)和一个矿,具有重要的生物活动,使这一化合物对医药化学具有兴趣; 氮原子上的二甲基替代会增强溶性,并可能影响其药用动力特性; 这种复合体可能表现出抗微生物或抗病毒活动,正如许多磺酰胺所做的那样,其碘分成分也可能带来额外的治疗利益; 总体而言,N,N-二甲基4,5-Diiodo-1H-imidazole-1-Sulfonamidine是一种复杂的分子,有可能用于药物,特别是在开发新的治疗剂方面.
- 英文名称N,N-Dimethyl 4,5-Diiodo-1H-Imidazole-1-Sulfonamide
- 中文名称N,N-二甲基4,5-二碘-1H-咪唑-1-磺酰胺
- IUPAC名称4,5-diiodo-N,N-dimethyl-1H-imidazole-1-sulfonamide
- 其它别名N,N-二甲基-4,5-二碘-1H-咪唑-1-磺酰胺; 4,5-Diiodo-N,N-Dimethyl-1H-Imidazole-1-Sulfonamide
- CAS编号198127-92-3
- MFCD编号:MFCD02179532
- 分子式:C5H7I2N3O2S分子量:427.01
- 产品CID: 1008404
- 产品分类有机原料→分子砌块→芳杂环类化合物→咪唑类化合物
相似化合物
135773-25-0 78162-58-0 140174-48-7物理性质
MSDS等安全信息
上下游产品
4,5-diiodo-1H-imidazole dimethylamino sulfonyl chloride5-(3,4-dimethoxybenzyl)-1-dimethylsulfamoyl-4-iodoimidazole 4-iodo-N,N-dimethyl-1H-imidazole-1-sulfonamide 5-(3,4-dimethoxybenzyl)-1-dimethylsulfamoylimidazole 2-(3,4-dichloro-α-hydroxybenzyl)-5-(3,4-dimethoxybenzyl)-1-dimethylsulfamoylimidazole合成工艺路线路线简述
📜4,5-二碘咪唑,二甲胺基磺酰氯置于sodium Hydride体系中,用 四氢呋喃 用作溶剂,以62%的收率获得n,N-二甲基-4,5-二碘-1H-咪唑-1-磺酰胺
参考文献:Synthesis And Diels−alder Reactions Of 4-Vinylimidazoles
标题:Synthesis And Diels−alder Reactions Of 4-Vinylimidazoles
摘要:[graphics]The Synthesis Of Several 4-Vinylimidazoles Via Stille Cross-Coupling Reactions Of The Corresponding Protected 4-Iodoimidazoles With Tributylvinylstannane Is Described,These Heterocyclic Dienes Are Shown To Be Effective Partners In The Diels-Alder Reaction,Providing Adducts In Good Yield Acid Exhibiting Useful Levels Of Isomer Selectivity And Stereoselectivity (Endo/exo).
Doi:10.1021/ol015687M
海关参考信息
- 2921199090-其他无环单胺
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- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Total Synthesis Of The Nagelamides - Synthetic Studies Toward The Reported Structure Of Nagelamide D And Nagelamide E Framework作者:Manojkumar R. Bhandari,Apsara K. Herath,Sivappa Rasapalli,Muhammed Yousufuddin,Carl J. Lovely |发布日期:2020.10.16
摘要:Closely Related Oroidin Alkaloids, Supporting The Structure Of The Synthetic Material. The Structure Of The Synthetic Material Was Further Corroborated By Obtaining An X-Ray Crystal Structure Of A Derivative. Electrocyclization Of An Advanced Precursor Affords A Dihydrobenzimidazole, Which Is Expected To Serve As A Key Intermediate En Route To Nagelamide E And Ageliferin.
合成参考文献
摘要:Andersson, C.-M.; Andersson, M., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 42.
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