CAS: 18649-93-9; (5R,8S,9S,10S,11S,14R)-17-((2R,4S)-4-((R)-3,3-Dimethyloxiran-2-yl)-4-Hydroxybutan-2-yl)-11-Hydroxy-4,4,8,10,14-Pentamethyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-Tetradecahydro-3H-Cyclopenta[a]Phenanthren-3-One
该化合物是自然产生的三叶质化合物,主要来自Alisma orentale植物(通常称为水板)的硫酸盐,其特点是复杂的四环结构,有助于其生物活动.Alisol B具有各种药理特性,包括抗炎,肝脏保护,和尿道效应,使其对传统医学和潜在的治疗应用感兴趣.该物质通常以白到白粉的形式出现,在乙醇和乙醇等有机溶剂中溶解,但水溶解程度较低.其各种生物系统中的行动和功效机制是正在进行的研究的主题,突出其作为药物开发中铅化合物的潜力.此外,Alisol B的安全特征和毒性是其用于药剂制剂的重要考虑因素.
- 英文名称(5R,8S,9S,10S,11S,14R)-17-((2R,4S)-4-((R)-3,3-Dimethyloxiran-2-yl)-4-Hydroxybutan-2-yl)-11-Hydroxy-4,4,8,10,14-Pentamethyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-Tetradecahydro-3H-Cyclopenta[a]Phenanthren-3-One
- 中文名称泽泻醇 B
- IUPAC名称(5R,8S,9S,10S,11S,14R)-17-((2R,4S)-4-((R)-3,3-dimethyloxiran-2-yl)-4-hydroxybutan-2-yl)-11-hydroxy-4,4,8,10,14-pentamethyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
- 其它别名Dammar-13(17)-En-3-One, 24,25-Epoxy-11,23-Dihydroxy-,(8A,9B,11B,14B,23S,24R)-; Alisolb; Alisol-B; Alisol B
- CAS编号18649-93-9
- MFCD编号:MFCD24369682
- 分子式:C30H48O4分子量:472.71
- 产品CID: 951124
- 产品分类生物化工 → 提取物 → 植物提取物
物理性质
MSDS等安全信息
上下游产品
CAS号18674-16-3 泽泻醇 A 24-醋酸酯合成工艺路线路线简述
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2022162188-A1
优先权日:2019-01-15
标 题:Isoprenoids and methods of making thereof
发明人：WILLIAMS GAVIN; LUND SEAN; HALL RACHAEL
权利人:UNIV NORTH CAROLINA STATE
摘要:Disclosed are methods for preparing isoprenoid subunits, as well as methods of employing these isoprenoid subunits for the synthesis of isoprenoids. Also provided are isoprenoids prepared using the methods described herein.
专利号:EP-4376865-A2
优先权日:2021-07-26
标题 :Pulse protein-based composition for activating the synthesis of fgf19
专利号:WO-2023006248-A2
优先权日:2021-07-26
标 题 :Method for activating the synthesis of fgf19
专利号:CN-117164658-B
优先权日:2023-09-04
标题:A derivative of alismatol B, its synthesis method, and its pharmaceutical composition and application
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/s13318-018-0476-8
摘要:Wu H, Wang X, Deng J, Quan S, Wang Q, Li W. Pharmacokinetic Profiling of Butylidenephthalide and Alisol B in Danggui-Shaoyao-San in Rats. European Journal of Drug Metabolism and Pharmacokinetics. 2018 Apr 27;43(6):645–53. doi: 10.1007/s13318-018-0476-8.
参考文献:10.1016/j.phymed.2018.04.006
摘要:Liao M, Shang H, Li Y, Li T, Wang M, Zheng Y, Hou W, Liu C. An integrated approach to uncover quality marker underlying the effects of Alisma orientale on lipid metabolism, using chemical analysis and network pharmacology. Phytomedicine. 2018 Jun 01;45():93–104. doi: 10.1016/j.phymed.2018.04.006.
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