CAS: 13327-31-6; 6-Iodoquinoline

相似化合物

79476-07-6 16560-43-3 1006-47-9

上下游产品

CAS号580-15-4 6-氨基喹啉 | CAS号406463-06-7 6-喹啉硼酸频哪醇酯 | CAS号943541-40-0 2,2-二氟-2-(喹啉-6-... | CAS号612-95-3 6-苯基喹啉 | CAS号943541-39-7 2,2-二氟-2-(喹啉-6-基)乙酰肼 | CAS号612-79-3 6,6'-BIQUINOLINE

6-氨基喹啉置于三氟甲磺酸,Sodium Nitrite,Potassium Iodide体系中,用 正己烷,二甲基亚砜,水 用作溶剂,化学反应 1.17H,以79%的收率获得6-碘喹啉
参考文献:通过溶液中氨基吡啶和氨基喹啉的一锅重氮化,新型便捷合成吡啶基和喹啉基三氟甲磺酸酯和甲苯磺酸酯
标题:通过溶液中氨基吡啶和氨基喹啉的一锅重氮化,新型便捷合成吡啶基和喹啉基三氟甲磺酸酯和甲苯磺酸酯
摘要:摘要 开发了第一种有效且简单的方法,用于将2-,3-和4-氨基吡啶,2,6-二氨基吡啶和2-氨基喹啉直接单锅转化用作溶剂中相应的吡啶基和喹啉基三氟甲烷磺酸盐和甲苯磺酸盐.该方法涉及在三氟甲磺酸或对甲苯磺酸的存在下,在亚硝酸钠的混合己烷-Dmso或己烷-Dmf溶液中用亚硝酸钠重氮化杂环胺. 开发了第一种有效且简单的方法,用于将2-,3-和4-氨基吡啶,2,6-二氨基吡啶和2-氨基喹啉直接单锅转化用作溶剂中相应的吡啶基和喹啉基三氟甲烷磺酸盐和甲苯磺酸盐.该方法涉及在三氟甲磺酸或对甲苯磺酸的存在下,在亚硝酸钠的混合己烷-Dmso或己烷-Dmf溶液中用亚硝酸钠重氮化杂环胺.
Doi:10.1055/s-0035-1560392

专利信息

专利号:US-10759743-B2
优先权日:2016-10-24
标 题 :Pd-catalyzed γ-C(sp3)-H arylation / heteroarylation of free amines
发明人：YU JIN-QUAN
权利人:SCRIPPS RESEARCH INST
摘要:Pd(II)-catalyzed g-G(sp3)-H arylation or heteroarylation of primary amines is realized by using 2-hydroxynicotinaldehyde as a catalytic transient directing group. Importantly, the catalyst and the directing group loading can be lowered to 2% and 4% respectively, thus demonstrating high efficiency of this newly designed transient directing group. Heterocyclic aryl iodides are also compatible with this reaction. Furthermore, swift synthesis of 1,2,3,4-tetrahydronaphthyridine derivatives is accomplished using this reaction.

专利号:WO-2023061999-A1
优先权日:2021-10-12
标 题 :Process for preparing a phenolic hydrocarbon
发明人：CORNELLA JOSEP; LE VAILLANT FRANCK
权利人:STUDIENGESELLSCHAFT KOHLE GGMBH
摘要:The present invention discloses a distinct mode of action of a nickel catalyst to forge C-0 bonds to unlock the mild utilization of N2O as O-atom transfer reagent in the synthesis of complex phenols from the corresponding aryl halides.

专利号:US-2008119515-A1
优先权日:2003-03-10
标题:Heterocyclic Kinase Inhibitors: Methods of Use and Synthesis
发明人：SIDDIQUI M ARSHAD; BELANGER DAVID B; DAI CHAOYANG; ZHAO LIANYUN
权利人:SIDDIQUI M ARSHAD; BELANGER DAVID B; DAI CHAOYANG; ZHAO LIANYUN
摘要:Inhibitors of kinases, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making kinase inhibitor compounds, methods of inhibiting kinase activity, and methods for treating disease or disease symptom.

专利号:WO-2004080463-A1
优先权日:2003-03-10
标题 :Heterocyclic kinase inhibitors: methods of use and synthesis
发明人：SIDDIQUI M ARSHAD; BELANGER DAVID; DAI CHAOYANG; ZHAO LIANYUN
权利人:NEOGENESIS PHARMACEUTICALS INC; SIDDIQUI M ARSHAD; BELANGER DAVID; DAI CHAOYANG; ZHAO LIANYUN
摘要:Inhibitors of kinases, compositions including the inhibitors, and methods of using the inhibitors and inhibitor compositions are described. The inhibitors and compositions including them are useful for treating disease or disease symptoms. The invention also provides for methods of making kinase inhibitor compounds, methods of inhibiting kinase activity, and methods for treating disease or disease symptom.

专利号:WO-2024185814-A1
优先权日:2023-03-06
标题:Method for producing aryl compound containing tritylsulfanyl group
发明人：OKAZOE TAKASHI; NOZAKI KYOKO; GATZENMEIER Tim; LIU YUE
权利人:AGC INC; UNIV TOKYO
摘要:The present invention provides: a substrate for achieving the highly efficient synthesis of an aryl compound containing a tritylsulfanyl group; a method for producing a compound containing an SF 5 group using the substrate; and others. The present invention is a method for producing an aryl compound containing a tritylsulfanyl group, the method comprising thiotritylating a halogenated aryl compound represented by general formula (1) [wherein A 1 represents an aryl group that may have a substituent or a heteroaryl group that may have a substituent; and X represents a halogen atom] using [(triphenylmethyl)sulfanyl]potassium or [(triphenylmethyl)sulfanyl]sodium to produce an aryl compound containing a tritylsulfanyl group, the aryl compound being represented by general formula (2) [wherein A 1 is the same as A 1 in general formula (1); and Ph represents a phenyl group].

专利号:CN-114716439-A
优先权日:2022-04-26
标题 :A method of copper-catalyzed synthesis of 6-thiopurine derivatives