CAS: 35367-31-8; Penfluron

该化合物是化学化合物,其结构复杂,包括一种以氟和三氟甲基组组成的苯胺核心,在苯环的2和6个位置上存在两个氟原子,会增强化合物的亲脂性,并可能影响其生物活动.以电子提取特性著称的三氟甲基组有助于化合物的总体再活动性和稳定性.由于氨功能组的存在,这种化合物可能表现出极化的显著特征,该化合物可以进行氢联结.此外,氟化组的独特组合可能会产生特定的药用特性,从而引起对药用化学的兴趣.其化学文摘号为35367-318,便于在化学数据库中识别和参考.

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2,6-difluorobenzoyl is°Cyanate (4-Trifluoromethyl-phenyl)-carbamic acid ethyl ester 4-trifluoromethylphenylamine 2,6-difluorobenzylamine

合成工艺路线路线简述

    📜对三氟甲基苯胺置于吡啶体系中,用 1,2-二氯乙烷 用作溶剂,化学反应 1.0H,反应生成氟幼脲
    参考文献:Synthesis And Insecticidal Evaluation Of Propesticides Of Benzoylphenylureas
    标题:Synthesis And Insecticidal Evaluation Of Propesticides Of Benzoylphenylureas
    摘要:Two Series Of Benzoylphenylurea Derivatives Were Synthesized As Candidate Propesticides By A Nucleophilic Addition Reaction Between 2,6-Difluronbenzoyl Isocyanate And N-Substitutedaniline. The New Compounds Were Identified By H-1 NMR Spectroscopy,Electron Ionization-Mass Spectrometry,And Elemental Analyses. The Bioactivities Of The New Compounds Were Evaluated. All Of The Propesticides Reported Here Were Soluble In Most Organic Solvents,And Their Hydrophobicities Were Improved Obviously. The Result Of The Bioactivities Of The New Compounds Against Oriental Armyworm Showed That Some Of The New Compounds Are Good As Compared To Diflubenzuron And Penfluron.
    Doi:10.1021/jf048561N

    海关参考信息

    专利信息


    专利号:WO-2011067757-A1
    优先权日:2009-12-06
    标题 :INSECTICIDAL COMPOSITIONS OF CHITIN SYNTHESIS INHIBITORS (CSIs) AND THE ENTOMOPATHOGENIC FUNGUS NOMURAEA RILEYI
    发明人:APPLEBAUM SHALOM W; ICHELCZIK DANA; BARAZANI AVNER
    权利人:MAKHTESHIM CHEM WORKS LTD; YISSUM RES DEV CO; APPLEBAUM SHALOM W; ICHELCZIK DANA; BARAZANI AVNER
    摘要:The present invention discloses a pesticidal composition comprising a combination of a chitin synthesis inhibitor (CSI) and the fungus Nomuraea rileyi, wherein this composition is insecticidally effective and contains an insecticidally effective amount of a chitin synthesis inhibitor and an insecticidally effective amount of the fungus Nomuraea rileyi. Also are disclosed a method of treating or preventing pest infestation in a plant or in an environment in which this plant is grown, by contacting the plant or environment with the pesticidal composition of the invention, and a method for reducing the amount of CSI required to control insects, and the use of the pesticidal composition of the invention in controlling insects in a plant or an environment of the plant.

    专利号:US-10906880-B2
    优先权日:2016-01-26
    标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
    发明人:FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
    权利人:UNIV NANKAI
    摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

    专利号:US-7628979-B1
    优先权日:2005-04-20
    标题 :Use of calco oil blue V in bait formulations for marking and controlling subterranean termites
    发明人:MORALES-RAMOS JUAN A; ROJAS MARIA G
    权利人:US AGRICULTURE
    摘要:Termite bait matrix containing cellulose, calco oil blue V (solvent blue 58 or 9,10-anthracenedione, 1,4-bis[(2-ethylhexyl)amino]), and optionally a termite toxicant (e.g., chitin synthesis inhibitor). Methods of monitoring termite activity in a region involving placing a termite bait matrix in the region and assessing the presence of termites at the site of the termite matrix, the termite bait matrix contains cellulose and 9,10-anthracenedione, 1,4-bis[(2-ethylhexyl)amino]. Methods of killing termites, involving placing a termite bait matrix in a termite habitat and allowing termites to feed on the bait matrix, the termite bait matrix contains cellulose, 9,10-anthracenedione, 1,4-bis[(2-ethylhexyl)amino], and a termite toxicant (e.g., chitin synthesis inhibitor).

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    专利号:WO-2021074311-A1
    优先权日:2019-10-16
    标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)

    专利号:EP-1771070-B1
    优先权日:2004-07-26
    标题:Mixtures of anthranilamide invertebrate pest control agents
    发明人:ANNAN ISAAC BILLY; HUGHES KENNETH ANDREW; LAHM GEORGE PHILIP; SELBY THOMAS PAUL; STEVENSON THOMAS MARTIN
    权利人:DU PONT
    摘要:Disclosed are mixtures and compositions for controlling invertebrate pests relating to combinations comprising (a) 3-bromo-N-[4-cyano-2-methyl-6­[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide, an N-oxide, or a salt thereof, Formula (1) and (b) at least one invertebrate pest control agent selected from neonicotinoids, cholinesterase inhibitors, sodium channel modulators, chitin synthesis inhibitors, ecdysone agonists, lipid biosynthesis inhibitors, macrocyclic lactones, GABA-regulated chloride channel blockers, juvenile hormone mimics, ryanodine receptor ligands, octopamine receptor ligands, mitochondrial electron transport inhibitors, nereistoxin analogs, pyridalyl, flonicamid, pymetrozine, dieldrin, metaflumizone, biological agents, and salts of the foregoing. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a mixture or composition of the invention.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1107/s1600536804023207
    摘要:Chen L, Song H, Wang Q, Huang R, Shang J, Mao C. 1-(2,6-Difluorobenzoyl)-3-[4-(trifluoromethyl)phenyl]urea. Acta Crystallogr E Struct Rep Online. 2004 Sep 30;60(10):o1865–7. doi: 10.1107/s1600536804023207.
    参考文献:10.1007/978-3-030-94949-5_9
    摘要:Advances in Integrated Pest Management Technology. 2022.
    参考文献:10.1023/a:1022575315413
    摘要:Thompson HM. Behavioural effects of pesticides in bees--their potential for use in risk assessment. Ecotoxicology. 2003 Feb;12(1-4):317–30. doi: 10.1023/a:1022575315413.
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