CAS: 263149-10-6; 4-Chloro-7-Hydroxy-6-Methoxyquinoline-3-Carbonitrile

该化合物是一种多用途的奎诺派衍生物,具有巨大的制药和农用化学研究潜力,其独特的结构,其基质上的氯,氢氧化和甲氧替代成分,增强了其反应性和结合性,使其成为合成生物活性化合物的宝贵中间体.硝基尔组的存在进一步扩大了其在热循环化学中的用途,使多种功能化.该复合物在标准条件下表现出极佳的稳定,确保合成应用的可靠性能.其独特的替代模式也有助于潜在的生物活动,包括药物发现中感兴趣的抗微生物和抗癌特性.这种quino衍生物的高纯度和定义明确的结构使它适合于精确的研究应用.

英文名称4-Chloro-7-Hydroxy-6-Methoxyquinoline-3-Carbonitrile
中文名称4-氯-7-羟基-6-甲氧-3-腈基喹啉
IUPAC名称4-chloro-7-hydroxy-6-methoxyquinoline-3-carbonitrile
其它别名3-喹啉,4-氯-7-羟基-6-甲氧基; 4-Chlor-7-Hydroxy-6-Methoxychinolin-3-Carbonitril
CAS编号263149-10-6
MFCD编号:MFCD09833973
分子式:C11H7ClN2O2
分子量:234.64
产品CID: 1235742
产品分类有机原料→分子砌块→芳杂环类化合物→喹啉类化合物

相似结构搜索
InChIKey: QWSGXXUZCAKURD-UHFFFAOYSA-N
InChI=1S/C11H7ClN2O2/c1-16-10-2-7-8(3-9(10)15)14-5-6(4-13)11(7)12/h2-3,5,15H,1H3…
计算化学: 氢键受体数4.0氢键供体数1.0可旋转键数1.0

相似化合物

214470-55-0 1415562-51-4 307353-95-3

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
危险品标志Xi

上下游产品

合成工艺路线路线简述

2-氨基-4-异丙氧基-5-甲氧基苯甲酸甲酯置于三氯化铝,三氯氧磷体系中,化学反应生成4-氯-7-羟基-6-甲氧基喹啉-3-甲腈
参考文献:Inhibitors Of Src Tyrosine Kinase: The Preparation And Structure-activity Relationship Of 4-Anilino-3-Cyanoquinolines And 4-Anilinoquinazolines
标题:Inhibitors Of Src Tyrosine Kinase: The Preparation And Structure-activity Relationship Of 4-Anilino-3-Cyanoquinolines And 4-Anilinoquinazolines
摘要:Src Is A Nonreceptor Tyrosine Kinase Involved In Signaling Pathways That Control Proliferation,Migration,And Angiogenesis. Increased Src Expression And Activity Are Associated With An Increase In Tumor Malignancy And Poor Prognosis. Several Quinolines And Quinazolines Were Identified As Potent And Selective Inhibitors Of Src Kinase Activity. (C) 2000 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0960-894X(00)00493-5