CAS: 25279-15-6; 12-Hydroxy-17-(5-(2-Hydroxypropan-2-yl)-2-Methyltetrahydrofuran-2-yl)-4,4,8,10,14-Pentamethylhexadecahydro-3H-Cyclopenta[a]Phenanthren-3-One
该化合物是三叶管化合物,其特点是复杂的多环结构,包括一个水坝骨骼.这种物质在C-3位置上具有一个氯酮功能组,C-20和C-24之间的一个环氧组,以及C-12和C-25位置上的氢氧基组,有助于其生物活动.(12b,24R)所显示的立体化学显示的原子的具体空间安排能够影响其与生物系统的互动.这种化合物经常因其潜在的药理特性,包括防炎,抗氧化剂和抗癌活动而研究其三叶管,多种功能组的存在增强了其再活性和溶解在各种溶剂中的溶解性,使其在医药化学和天然产品研究中具有兴趣.此外,该化合物的独特结构可能导致与细胞目标的具体互动,值得进一步调查其治疗潜力.
- 英文名称12-Hydroxy-17-(5-(2-Hydroxypropan-2-yl)-2-Methyltetrahydrofuran-2-yl)-4,4,8,10,14-Pentamethylhexadecahydro-3H-Cyclopenta[a]Phenanthren-3-One
- 中文名称20S,24R-环氧基-达马树脂-12,25-二醇-3-酮
- IUPAC名称12-hydroxy-17-(5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one
- 其它别名(20S,24R)-12β,25-Dihydroxy-20,24-Epoxydammarane-3-One; (20S,24R)-20,24-Epoxy-12β,25-Dihydroxydammaran-3-One; 3-Dehydropyxinol; 20S,24R-Epoxy-Dammar-12,25-Diol-3-One; Dammaran-3-One,20,24-Epoxy-12,25-Dihydroxy-, (12B,24R)- (9Ci); Dammaran-3-One, 20,24-Epoxy-12,25-Dihydroxy-, (12β,20S,24R)-; 20S,24R-Epoxydammara-12β,25-Diol-3-One
- CAS编号25279-15-6
- MFCD编号:MFCD20260352
- FDA UNII编号:RCA3293YRJ
- 分子式:C30H50O4分子量:474.73
- 产品CID: 1211842
- 产品分类天然产物 → 萜类
物理性质
MSDS等安全信息
上下游产品
Betulafolienetriol oxide (5R,8R,9R,10R,12R,13R,14R,17S)-17-[(2S,5R)-5-(1-Hydroxy-1-methyl-ethyl)-2-methyl-tetrahydro-furan-2-yl]-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthrene-3,12-diol 3,12-di-O-acetydammar-24-ene-3β,12β,20(S)-triol (20S,24)-epoxy-3β,12β-O-diacetyldammarane-25-ol合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1021/acsmedchemlett.9b00562
摘要:Sun Y, Fang X, Gao M, Wang C, Gao H, Bi W, Tang H, Cui Y, Zhang L, Fan H, Yu H, Yang G. Synthesis and Structure–Activity Relationship of Pyxinol Derivatives as Novel Anti-Inflammatory Agents. ACS Med. Chem. Lett. 2020 Feb 12;11(4):457–63. doi: 10.1021/acsmedchemlett.9b00562.
参考文献:10.1016/j.ejmech.2013.07.041
摘要:Zhou Z, Ma C, Zhang H, Bi Y, Chen X, Tian H, Xie X, Meng Q, Lewis PJ, Xu J. Synthesis and biological evaluation of novel ocotillol-type triterpenoid derivatives as antibacterial agents. European Journal of Medicinal Chemistry. 2013 Oct;68():444–53. doi: 10.1016/j.ejmech.2013.07.041.
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