CAS: 24393-49-5; Ethyl 3-(P-Tolyl)Acrylate

该化合物是有机化合物,其特点是丙烯酸结构,包括一个乙烯基组和一个酯功能组;该化合物一般是无色的,可粉色黄色液体,具有典型的气味;可溶于乙醇和乙醚等有机溶剂,但在水中溶解性有限;四甲基苯基组的存在有助于其芳香特性,影响其反应性和潜在应用;乙酰四甲基联苯丙烯基经常用于聚合化学,特别是生产涂层,粘合剂和其他材料,因为其能够进行聚合;必须谨慎处理这一化合物,因为它可能给健康带来危险,如皮肤和眼刺激;此外,最好参考安全数据表,以了解具体的处理和储存准则;总的来说,该化合物在各种工业应用中,特别是在功能聚合聚合物中,具有重大意义.

英文名称Ethyl 3-(P-Tolyl)Acrylate
中文名称反式-4-甲基肉桂酸乙酯
IUPAC名称ethyl (E)-3-(p-tolyl)acrylate
其它别名(E)-3-(4-Methylphenyl)Propenoic Acid Ethyl Ester; (E)-4-Methylcinnamic Acid Ethyl Ester; (E)-Methyl 3-(P-Tolyl)Acrylate; Ozagrel Impurity 5; 4-Methyl-Trans-Cinnamic Acid Ethyl Ester; P-Methylcinnamic Acid Ethyl Ester; Ethyl (E)-4-Methylcinnamate; Ethyl (E)-3-(4-Methylphenyl)-2-Propenoate
CAS编号24393-49-5
MFCD编号:MFCD00182491
分子式:C12H14O2分子量:190.24
产品CID: 1191246

相似结构搜索
产品信息参考;;;;
InChIKey: IMKVSWPEZCELRM-CMDGGOBGSA-N
InChI=1S/C12H14O2/c1-3-14-12(13)9-8-11-6-4-10(2)5-7-11/h4-9H,3H2,1-2H3/b9-8+
计算化学: 氢键受体数2.0氢键供体数*可旋转键数4.0

MSDS等安全信息

警示词Warning
危险描述H302-H315-H319-H335-
防范说明P261-P280-P301+P312-P302+P352-P305+P351+P338-
安全声明H303+H313+H333

上下游产品

piperidine (4-methyl-benzylidene)-malonic acid monoethyl ester ethanol trans-p-methylcinnamic acidp-methylcinnamyl alcohol 4-Cyano-4-naphthalen-1-yl-3-p-tolyl-butyric acid ethyl ester 3-(3,4-Dimethoxy-phenyl)-3-p-tolyl-propionic acid ethyl ester trans-2-Ethoxycarbonyl-3-(4-methyl-phenyl)-pyrrolidon-5

合成工艺路线路线简述

104-87-0 + 188945-44-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Benzyltrimethylammonium Hydroxide Solvents: Methanol,Tetrahydrofuran; -78 °C; 15 Min,-78 °C1.2 Solvents: Tetrahydrofuran; -78 °C; 10 H,-78 °C1.3 Reagents: Ammonium Chloride Solvents: Water
标题:Substituent Effects Of Cis-Cinnamic Acid Analogues As Plant Growth Inhibitors
作者:Nishikawa,Keisuke; Fukuda,Hiroshi; Abe,Masato; Nakanishi,Kazunari; Taniguchi,Tomoya; Et Al
参考文献:Phytochemistry (Elsevier) 日期:2013 卷标:96 页码:132-147]

104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Triphenylphosphine Catalysts: Iron Tetraphenylporphyrin Chloride Solvents: Toluene; 2 Min,Rt; 0.5 H,80 °C
标题:Iron(Iii) And Ruthenium(Ii) Porphyrin Complex-Catalyzed Selective Olefination Of Aldehydes With Ethyl Diazoacetate
作者:Chen,Ying; Huang,Lingyu; Ranade,Meera A.; Zhang,X. Peter
参考文献:Journal Of Organic Chemistry 日期:2003 卷标:68(9) 页码:3714-3717]

589-18-4 + 1099-45-2 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Oxygen Catalysts: Manganese Potassium Oxide (Mn8Ko16) Solvents: Toluene; 4 H,110 °C
标题:Oms-2 For Aerobic,Catalytic,One-Pot Alcohol Oxidation-Wittig Reactions: Efficient Access To α,β-Unsaturated Esters
作者:Kona,Jagadeswara R.; King'Ondu,Cecil K.; Howell,Amy R.; Suib,Steven L.
参考文献:Chemcatchem 日期:2014 卷标:6(3) 页码:749-752]

105-39-5 + 104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Triphenylphosphine,Diisopropylethylamine Catalysts: Silica; 6 H,90 °C
标题:Silica Gel-Mediated Organic Reactions Under Organic Solvent-Free Conditions
作者:Onitsuka,Satoaki; Jin,Yong Zhi; Shaikh,Ajam C.; Furuno,Hiroshi; Inanaga,Junji
参考文献:Molecules 日期:2012 卷标:17 页码:11469-11483]

104-87-0 + 105-36-2 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: 2564764-59-4 Solvents: Acetonitrile; 3 H,60 °C1.2 Reagents: Silanamine,1,1,1-Trimethyl-N,N-Bis(Trimethylsilyl)-,Potassium Salt (1:1); 0 °C; 6 H,60 °C1.3 0 °C; 3 H,60 °C
标题:Phosphorus-Recycling Wittig Reaction: Design And Facile Synthesis Of A Fluorous Phosphine And Its Reusable Process In The Wittig Reaction
作者:Yamamoto,Yuki; Kawaguchi,Shin-Ichi; Nishimura,Misaki; Sato,Yuki; Shimada,Yoshihisa; Et Al
参考文献:Journal Of Organic Chemistry 日期:2020 卷标:85(22) 页码:14684-14696]

867-13-0 + 104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1,8-Diazabicyclo[5.4.0]Undec-7-Ene; 4 H,Rt
标题:Accessing Dihydro-1,2-Oxazine Via Cloke-Wilson Type Annulation Of Cyclopropyl Carbonyls: Application Towards The Diastereoselective Synthesis Of Pyrrolo[1,2-B][1,2]Oxazine
作者:Kumar,Pankaj; Kumar,Rakesh; Banerjee,Prabal
参考文献:Journal Of Organic Chemistry 日期:2020 卷标:85(10) 页码:6535-6550]

104-87-0 + 105-36-2 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Triphenylsilane,Diisopropylethylamine Catalysts: 1-Phenylarsolane Solvents: Toluene; 24 H,100 °C
标题:Systematic Study On The Catalytic Arsa-Wittig Reaction
作者:Inaba,Ryoto; Kawashima,Ikuo; Fujii,Toshiki; Yumura,Takashi; Imoto,Hiroaki; Et Al
参考文献:Chemistry - A European Journal 日期:2020 卷标:26(59) 页码:13400-13407]

52188-06-4 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Manganese,Water Catalysts: Palladium Diacetate Solvents: Acetonitrile; 24 H,25 °C
标题:Water As A Hydrogenating Agent: Stereodivergent Pd-Catalyzed Semihydrogenation Of Alkynes
作者:Zhao,Chuan-Qi; Chen,Yue-Gang; Qiu,Hui; Wei,Lei; Fang,Ping; Et Al
参考文献:Organic Letters 日期:2019 卷标:21(5) 页码:1412-1416]

104-87-0 + 1191236-16-4 = 24393-49-5 + 97585-04-1
反应条件:1.1 Solvents: Dimethyl Sulfoxide; 4 H,30 °C1.2 Solvents: Water; 5 Min,30 °C
标题:Efficient Alkenation Of Aldehydes And Ketones To α,β-Unsaturated Esters Using α,α-Bis(Dimethylsilyl)-Substituted Esters
作者:Miura,Katsukiyo; Ebine,Masaru; Ootsuka,Kazunori; Ichikawa,Junji; Hosomi,Akira
参考文献:Chemistry Letters 日期:2009 卷标:38(8) 页码:832-833]

589-18-4 + 105-36-2 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Triphenylphosphine,Manganic Acid (H2Mno4),Barium Salt (1:1) Solvents: Acetonitrile; 24 H,80 °C
标题:Tandem Oxidation-Wittig Reaction Using Nanocrystalline Barium Manganate (Bamno4); An Improved One-Pot Protocol
作者:Gholinejad,Mohammad; Firouzabadi,Habib; Bahrami,Maedeh; Najera,Carmen
参考文献:Tetrahedron Letters 日期:2016 卷标:57(33) 页码:3773-3775]

867-13-0 + 104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1,8-Diazabicyclo[5.4.0]Undec-7-Ene; 4 H,Rt
标题:Organocatalytic Activation Of Donor-Acceptor Cyclopropanes: A Tandem (3 + 3)-Cycloaddition/aryl Migration Toward The Synthesis Of Enantioenriched Tetrahydropyridazines
作者:Hazra,Arijit; Dey,Raghunath; Kushwaha,Apoorv; Dhilip Kumar,T. J.; Banerjee,Prabal
参考文献:Organic Letters 日期:2023 卷标:25(29) 页码:5470-5475]

867-13-0 + 104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1,8-Diazabicyclo[5.4.0]Undec-7-Ene; 4 H,Rt
标题:Accessing Complex Tetrahydrofurobenzo-Pyran/furan Scaffolds Via Lewis-Acid Catalyzed Bicyclization Of Cyclopropane Carbaldehydes With Quinone Methides/esters
作者:Kaur,Navpreet; Kumar,Pankaj; Dutt,Shiv; Banerjee,Prabal
参考文献:Journal Of Organic Chemistry 日期:2022 卷标:87(12) 页码:7905-7918]

867-13-0 + 104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1,8-Diazabicyclo[5.4.0]Undec-7-Ene; 4 H,Rt
标题:Metal-Free Domino Cloke-Wilson Rearrangement-Hydration-Dimerization Of Cyclopropane Carbaldehydes: A Facile Access To Oxybis(2-Aryltetrahydrofuran) Derivatives
作者:Dey,Raghunath; Rajput,Shruti; Banerjee,Prabal
参考文献:Tetrahedron 日期:2020 卷标:76(15)]

867-13-0 + 104-87-0 = 24393-49-5 + 97585-04-1
反应条件:1.1 Reagents: Potassium Carbonate Catalysts: 1,8-Diazabicyclo[5.4.0]Undec-7-Ene; 4 H,Rt
标题:Exploitation Of Cyclopropane Carbaldehydes To Prins Cyclization: Quick Access To (E)-Hexahydrooxonine And Octahydrocyclopenta[b]Pyran
作者:Kumar,Pankaj; Dey,Raghunath; Banerjee,Prabal
参考文献:Organic Letters 日期:2018 卷标:20(17) 页码:5163-5166