专利号:US-8735391-B2 优先权日:2008-09-26 标 题 :Synthesis of functionalized octahydro-isoquinolin-1-one-8-carboxamides, octahydro-isoquinolin-1-one-8-carboxylic esters and analogs, and therapeutic methods 发明人:AUBE JEFFREY; ROTH BRYAN L; GHOSH PARTHA; FRANKOWSKI KEVIN J 权利人:AUBE JEFFREY; ROTH BRYAN L; GHOSH PARTHA; FRANKOWSKI KEVIN J; UNIV KANSAS 摘要:A functionalized polycyclic compound can have a structure of Formula 1 or salt, prodrug, analog, or derivative thereof, which compound can be prepared by providing a diene; reacting the diene with a dienophile under sufficient conditions for a combined Diels-Alder/acylation reaction so as to provide a polycyclic compound having a carboxylic acid; and coupling the carboxylic acid with an amine-containing compound or a hydroxyl-containing compound so as to form an amide or an ester and producing a compound having a structure of Formula 1. The compound can be used for modulating an opioid receptor, which can be conducted by administering to an opioid receptor a functionalized polycyclic compound as described herein in an effective amount to modulate the functionality of the opioid receptor. Such opioid modulation can provide a biological benefit to a subject.
专利号:US-9452425-B2 优先权日:2002-09-26 标 题 :Compositions containing ionic liquids and their uses, in particular in organic synthesis 发明人:VAULTIER MICHEL; GMOUH SAID 权利人:VAULTIER MICHEL; GMOUH SAID; CENTRE NAT RECH SCIENT; UNIV RENNES 摘要:An ionic liquid is used as liquid matrix for organic synthesis in homogeneous phase on soluble support, the ionic liquid being presented in liquid or solid form at ambient temperature, of formula A 1 + X 1 − , A 1 + representing a cation, functional or non-functional, or a mixture of cations in which either none of the cations is functional or at least one of the cations is functional, and X 1 − an anion, functional or non-functional, or a mixture of anions in which either none of the anions is functional or at least one of the anions is functional.
专利号:US-11807596-B2 优先权日:2017-10-26 标题:Thiol compounds, synthesis method therefor, and utilization of said thiol compounds 发明人:OKUMURA NAOTO; OTSUKA AKIHITO; KUMANO TAKESHI; FUJIKAWA KAZUYUKI; ARAKI YUSUKE 权利人:SHIKOKU CHEM 摘要:The purpose of the present invention is to provide: novel thiol compounds; a method for synthesizing said thiol compounds; curing agents containing said thiol compounds; resin compositions containing said thiol compounds and an epoxy compound; and resin compositions containing said thiol compounds and an ene compound having a carbon-carbon double bond in a molecule. Furthermore, the purpose of the present invention is to provide adhesives and sealants having these resin compositions as ingredients. The thiol compounds of the present invention are represented by chemical formula (I) to chemical formula (VII).
专利号:CN-102125875-B 优先权日:2011-01-20 标 题 :Application of ferroceneimine cyclopalladium-phosphine adducts in the synthesis of unsymmetrical biaryl compounds
专利号:CN-113652705-B 优先权日:2021-06-23 标题:A kind of method for N-hydroxyphthalimide catalyzed electrolytic synthesis of fluorenone
专利号:CN-102125875-A 优先权日:2011-01-20 标 题 :Application of ferroceneimine cyclopalladium-phosphine adducts in the synthesis of unsymmetrical biaryl compounds
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