CAS: 1268521-85-2; Trans-3-Hydroxycyclobutanecarboxylic Acid
该化合物是一种具有氢氧基组和转基因功能的有机环丁烷衍生物,该化合物是有机合成的多功能构件,特别是用于制备药用活分子和精细化学物.其硬性环丁烷环和立体化学纯度为研究结构活动关系和设计受限制的类似物提供了宝贵价值.这种跨式配置加强了稳定性和影响再活动,在不对称合成和药用化学应用方面提供了优势.高纯度和定义明确的立体化学确保了研究和工业工艺的再生性.适合用于浸泡性微生物,催化剂和生物活性化合物开发.
- 英文名称Trans-3-Hydroxycyclobutanecarboxylic Acid
- 中文名称反式-3-羟基环丁烷甲酸
- IUPAC名称(1r,3r)-3-hydroxycyclobutane-1-carboxylic acid
- 其它别名(1R,3R)-3-羟基环丁烷-1-羧酸; Rac-(1R,3R)-3-Hydroxycyclobutane-1-Carboxylic Acid, Trans
- CAS编号1268521-85-2
- MFCD编号:MFCD17676395
- EINECS号:885-903-5
- 分子式:C5H8O3分子量:116.12
- 产品CID: 425670
- 产品分类有机原料→分子砌块→脂肪环类化合物→环丁烷类化合物
相似化合物
63485-51-8 552849-33-9 4958-02-5物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
海关参考信息
- 2905122000-异丙醇
2905399002-1,4-丁二醇
2912110000-甲醛
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专利信息
专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.
专利号:DK-2725028-T3
优先权日:2008-10-22
标题:Substituted pyrazolo [1,5-a] pyrimidine compounds as intermediates in the synthesis of kinase inhibitors TRK
专利号:EP-2725028-A1
优先权日:2008-10-22
标题 :Substituted pyrazolo[1,5-]pyrimidine compounds as intermediates in the synthesis of TRK kinase inhibitors
专利号:EP-2725028-B1
优先权日:2008-10-22
标题 :Substituted pyrazolo[1,5-]pyrimidine compounds as intermediates in the synthesis of TRK kinase inhibitors
专利号:HU-E030413-T2
优先权日:2008-10-22
标 题:Substituted pyrazolo[1,5-]pyrimidine compounds as intermediates in the synthesis of TRK kinase inhibitors
专利号:ES-2588504-T3
优先权日:2008-10-22
标题 :Pyrazolo [1,5-a] pyrimidine compounds substituted as intermediates in the synthesis of TRK kinase inhibitors
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1021/acs.jmedchem.7b01351
摘要:Krall J, Jensen CH, Bavo F, Falk-Petersen CB, Haugaard AS, Vogensen SB, Tian Y, Nittegaard-Nielsen M, Sigurdardóttir SB, Kehler J, Kongstad KT, Gloriam DE, Clausen RP, Harpsøe K, Wellendorph P, Frølund B. Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs. J Med Chem. 2017 Nov 09;60(21):9022–39. doi: 10.1021/acs.jmedchem.7b01351.
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