CAS: 1234480-84-2; 2-((2-Methoxy-4-(4-(4-Methylpiperazin-1-yl)Piperidine-1-Carbonyl)Phenyl)Amino)-5,11-Dimethyl-5H-Benzo[e]Pyrimido[5,4-B][1,4]Diazepin-6(11H)-One

主要参考文献

1: Smith GA, Jansson J, Rocha EM, Osborn T, Hallett PJ, Isacson O. Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition. Mol Neurobiol. 2015 Sep 23. [Epub ahead of print] [Epub ahead of print] doi: 10.1021/jm5018779. Epub 2015 May 1. doi: 10.1371/journal.pone.0118947. eCollection 2015.
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7: Weygant N, Qu D, Berry WL, May R, Chandrakesan P, Owen DB, Sureban SM, Ali N, Janknecht R, Houchen CW. Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1. Mol Cancer. 2014 May 6;13:103. doi: 10.1186/1476-4598-13-103.

合成参考文献

参考文献:10.1186/1476-4598-13-103
摘要:Weygant N, Qu D, Berry WL, May R, Chandrakesan P, Owen DB, Sureban SM, Ali N, Janknecht R, Houchen CW. Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1. Molecular Cancer. 2014 May 06;13(1):103. doi: 10.1186/1476-4598-13-103.