CAS: 63071-03-4; 2-Methoxy-6-Methylpyridine

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CAS号3279-76-3 2-羟基-6-甲基吡啶 | CAS号74-88-4 碘甲烷 | CAS号420-37-1 三甲基氧鎓四氟硼酸 | CAS号407-22-7 2-氟-6-甲基吡啶 | CAS号18368-63-3 2-氯-6-甲基吡啶 | CAS号124-41-4 甲醇钠 | CAS号5315-25-3 2-溴-6-甲基吡啶 | CAS号67-56-1 甲醇 | CAS号1824-81-3 2-氨基-6-甲基吡啶 | CAS号109-06-8 2-甲基吡啶 | CAS号3279-76-3 2-羟基-6-甲基吡啶 | CAS号195819-17-1 2-(6-甲氧基吡啶-2-基)乙醇 | CAS号18368-63-3 2-氯-6-甲基吡啶 | CAS号5467-69-6 2-甲氧基-5-硝基-6-甲基吡啶 | CAS号156094-77-8 6-甲氧基-2-甲基 烟醛 | CAS号126717-59-7 2-甲氧基-5-溴-6-甲基吡啶 | CAS号63071-04-5 Pyridine,2-meth... | CAS号510748-41-1 2-(3-bromo-6-me...

2-氟-6-甲基吡啶 反应生成 2-甲氧基-6-甲基吡啶
参考文献:4-(2-Butylamino)-2,7-Dimethyl-8-(2-Methyl-6-Methoxypyrid-3-yl) Pyrazolo-[1,5-A]-1,3,5-Triazine,Its Enantiomers And Pharmaceutically Acceptable Salts As Corticotropin Releasing Factor Receptor Ligands
标题:4-(2-Butylamino)-2,7-Dimethyl-8-(2-Methyl-6-Methoxypyrid-3-yl) Pyrazolo-[1,5-A]-1,3,5-Triazine,Its Enantiomers And Pharmaceutically Acceptable Salts As Corticotropin Releasing Factor Receptor Ligands
摘要:Corticotropin Releasing Factor (Crf)拮抗剂的化学式(I):1及其在治疗焦虑,抑郁和其他精神,神经系统疾病方面的应用,以及治疗与心理病理障碍和压力相关的免疫,心血管或心脏相关疾病和结肠过敏反应.

专利信息

专利号:US-9221821-B2
优先权日:2012-06-05
标题:Methods for the synthesis of 1,3-substituted aminouracils and other xanthine-related compounds
发明人：DIEP NHUT; KALYAN YURIY B
权利人:FOREST LAB HOLDINGS LTD; FOREST LAB HOLDINGS LTD
摘要:Methods for the synthesis of disubstituted aminouracils and xanthine and/or xanthine-related compounds are provided.

专利号:WO-2023086801-A1
优先权日:2021-11-09
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-9676783-B2
优先权日:2008-10-22
标 题:Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds
发明人：HAAS JULIA; ANDREWS STEVEN W; JIANG YUTONG; ZHANG GAN
权利人:ARRAY BIOPHARMA INC
摘要:Compounds useful in the synthesis of compounds for treating pain, cancer, inflammation, neurodegenerative disease or Typanosoma cruzi infection in a mammal.

专利号:EP-3904354-A1
优先权日:2020-04-30
标 题:New imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I)n nwherein R 1 represents a (C 1 -C 6 )alkyl group, a spiro(C 5 -C 11 )bicyclic ring, a fused phenyl group, a substituted phenyl group, a R'-L- group, wherein L is either a single bond or a (Ci-C3)alkanediyl group, and R' represents a (C 3 -C 8 )cycloalkyl group, a bridged (C6-C 10 )cycloalkyl group, a (C 3 -C 8 )heterocycloalkyl group, or a (C 3 -C 8 )heteroaryl group, or a R'-L- group wherein L is a (Ci-C3)alkanediyl group, and R' is a an optionally substituted phenyl group or any of its pharmaceutically acceptable salt. n The present invention further relates to a composition comprising a compound of formula (I) and a process for manufacturing said compound as well as its synthesis intermediates. n It also relates to said compound for use as a medicament, in particular in the treatment and/or prevention of cognitive deficits associated with Down syndrome; Alzheimer's disease; dementia; tauopathies; Parkinson's disease; CDKL5 Deficiency Disorder; Phelan-McDermid syndrome; autism; diabetes; regulation of folate and methionine metabolism; osteoarthritis; Duchenne muscular dystrophy; several cancers; neuroinflammation, anemia and infections and for regulating body temperature.

专利号:US-8987195-B2
优先权日:2012-08-08
标 题:HCV NS3 protease inhibitors
发明人：BARA THOMAS; BHAT SATHESH; BISWAS DIPSHIKHA; BROCKUNIER LINDA; BURNETT DUANE A; CHACKALAMANNIL SAMUEL; CHELLIAH MARIAPPAN V; CHEN AUSTIN; CLASBY MARTIN; COLANDREA VINCE J; GUO ZHUYAN; HAN YONGXIN; JAYNE CHARLES; JOSIEN HUBERT; MARCANTONIO KAREN; MIAO SHOUWU; NEELAMKAVIL SANTHOSH; PINTO PATRICK; RAJAGOPALAN MURALI; SHAH UNMESH; VELAZQUEZ FRANCISCO; VENKATRAMAN SRIKANTH; XIA YAN
权利人:MERCK SHARP & DOHME; MERCK CANADA INC
摘要:The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.

专利号:US-8466287-B2
优先权日:2005-06-09
标题 :Process for producing tricyclic ketone
发明人：NISHIYAMA HIROYUKI; SAWADA SEIGO
权利人:NISHIYAMA HIROYUKI; SAWADA SEIGO; YAKULT HONSHA KK
摘要:In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresponds to a CDE ring moiety of a camptothecin (CPT) skeleton.