专利号:US-11225655-B2 优先权日:2010-04-16 标题:Bi-functional complexes and methods for making and using such complexes 发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK 权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS 摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
专利号:US-4711888-A 优先权日:1985-07-24 标 题:Hydroxy and alkoxy pyrimidines 发明人:WALKER FREDERICK J; LAMATTINA JOHN L 权利人:PFIZER 摘要:2-Amino-4-substituted-5-(hydroxy or alkoxy)pyrimidines, which may be 6-substituted, and derivatives thereof are inhibitors of leukotriene synthesis and are therefore useful for the treatment of pulmonary, inflammatory, allergic and cardiovascular diseases. The compounds are also cytoprotective and therefore useful in the treatment of peptic ulcers.
参考标题:Catalytic Enantioselective Synthesis Of Bicyclic Lactam N ,S -Acetals In One Pot By Cascade Transformations 作者:Kaiheng Zhang,Luca Deiana,Erik Svensson Grape,A. Ken Inge,Armando Córdova |发布日期:2019.8.7 摘要:A Versatile Strategy For The Enantioselective Synthesis Of Bicyclic Lactam N,S-Acetals By One-Pot Cascade Transformations Is Disclosed. The Transformation Of Readily Available Substrates Is Promote ...