CAS: 5852-10-8; 2-(7-Hydroxy-4-Methyl-2-Oxo-2H-Chromen-3-yl)Acetic Acid

上下游产品

CAS号5852-03-9 3-(2'-ethoxycar... | CAS号1115-30-6 乙酰琥珀酸二乙酯 | CAS号108-46-3 间苯二酚 | CAS号2107-78-0 二甲基伞形酮

📜2-(7-羟基-4-甲基-2-氧代-2H-色烯-3-基)乙酸甲酯置于sodium Hydroxide体系中,用 水,异丙醇 作为反应溶剂,以72%的收率获得产物7-羟基-4-甲基-3-香豆素乙酸
参考文献:改性香豆素.25.含有香豆素片段的n-酰基胞嘧啶衍生物
标题:改性香豆素.25.含有香豆素片段的n-酰基胞嘧啶衍生物
摘要:通过用香豆素-3-乙酸酰化制备新的修饰的胞嘧啶衍生物.
DOI:10.1007/s10600-007-0053-X

专利信息

专利号:US-5419966-A
优先权日:1991-06-10
标 题 :Solid support for synthesis of 3'-tailed oligonucleotides
发明人：REED MICHAEL W; MEYER JR RICH B; PETRIE CHARLES R; TABONE JOHN C
权利人:MICROPROBE CORP
摘要:A solid support for oligonucleotide synthesis has the structure where CPG represents a controlled pore glass matrix, the wavy line represents a carbon chain covalently linking the NH group with the controlled pore glass matrix, X is 2,2'-dimethoxytrityl or H, and R is alkyl, aryl, arylalkyl, heteroalkyl, or heteroaryl. The dimethoxytrityl group is removed from the solid support by treatment with acid, and the oligonucleotide is built, step-by-step in a conventional synthesizer after attachment of the 3' end of the first oligonucleotide unit to the hydroxyl function connected to the R group.

专利号:US-7541143-B2
优先权日:1997-02-20
标题 :Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
发明人：PACKARD BEVERLY; KOMORIYA AKIRA
权利人:ONCOIMMUNIN INC
摘要:The present invention provides for novel reagents whose fluorescence changes upon cleavage or a change in conformation of a backbone. The reagents comprise a backbone (e.g. nucleic acid, polypeptide, etc.) joining two fluorophores of the same species whereby the fluorophores form an H-dimer resulting in quenching of the fluorescence of the fluorophores. When the backbone is cleaved or changes conformation, the fluorophores are separated, no longer forming an H-type dimer, and are de-quenched thereby providing a detectable signal. The use of a single fluorophore rather than an “acceptor-donorâ€? fluoresecence resonance energy transfer system offers synthesis and performance advantages.

专利号:WO-9203464-A1
优先权日:1990-08-28
标题 :Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule

专利号:JP-3256539-B2
优先权日:1990-08-28
标 题:Solid support synthesis of 3'-tailed oligonucleotides via linking molecules

专利号:JP-H06500556-A
优先权日:1990-08-28
标题 :Solid-support synthesis of 3'-tailed oligonucleotides via linking molecules

专利号:EP-0547142-A1
优先权日:1990-08-28
标题 :Solid support synthesis of 3'-tailed oligonucleotides via a linking molecule