CAS: 55583-59-0; 2,5-Diamino-4,6-Dichloropyrimidine

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上下游产品

CAS号56830-58-1 2,5-二氨基-4,6-二羟基嘧啶盐酸盐 | CAS号171887-03-9 N-(2-氨基-4,6-二氯-... | CAS号10052-47-8 甲基三乙基氯化铵 | CAS号96-18-4 1,2,3-三氯丙烷 | CAS号91322-00-8 2,4,6-三氯嘧啶-5-胺 | CAS号171887-03-9 N-(2-氨基-4,6-二氯-... | CAS号50619-39-1 1,2-Cyclopentan... | CAS号6270-25-3 2,4,5-Pyrimidin...

5-氨基-2,4,6-三氯嘧啶置于氨,水体系中,化学反应生成 2,5-二氨基-4,6-二氯嘧啶
参考文献:Pyrimidines. Iv. The Synthesis Of Several New Chloro Substituted Pyrimidines1
标题:Pyrimidines. Iv. The Synthesis Of Several New Chloro Substituted Pyrimidines1
摘要:
DOI:10.1021/jo01371A010

专利信息

专利号:US-6646125-B1
优先权日:1997-10-14
标 题 :Process for the synthesis of chloropurine intermediates
发明人：JONES MARTIN FRANCIS; WALLIS CHRISTOPHER JOHN
权利人:SMITHKLINE BEECHAM CORP
摘要:The present invention relates to a process for the preparation of a carbocyclic purine nucleoside analogue of formula (I), its salts and pharmaceutically acceptable derivatives thereof which comprises hydrolysing a compound of formula (IV) wherein P is a protecting group, in the presence of an acid, condensing the product of formula (V) formed in situ in the presence of a base with a compound of formula (VI) followed by in situ ring closure of the resulting intermediate.

专利号:US-12054512-B2
优先权日:2017-11-10
标 题 :Sting modulator compounds, and methods of making and using
发明人：VYSKOCIL STEPAN; CIAVARRI JEFFREY; CULLIS COURTNEY; ENGLAND DYLAN BRADLEY; GOULD ALEXANDRA E; GREENSPAN PAUL; HU YONGBO; LANGSTON STEVEN; LI GANG; MIZUTANI HIROTAKE; OKANIWA MASANORI
权利人:TAKEDA PHARMACEUTICALS CO
摘要:The present disclosure provides STING modulators/agonists, and methods of synthesis and methods for using for the prophylaxis or treatment of cancer and other STING-related diseases.The present disclosure relates to a compound represented by the Formula (I):wherein each symbol is as defined in the description, or a pharmaceutically acceptable salt thereof.

专利号:US-2011124634-A1
优先权日:2008-05-13
标 题:Bioactive compounds for treatment of cancer and neurodegenerative diseases
发明人：SUN CONNIE L; LI XIAOYUAN
权利人:PONIARD PHARMACEUTICALS INC
摘要:The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.

专利号:TW-436488-B
优先权日:1997-10-14
标 题 :Process for the synthesis of chloropurine intermediates

专利号:WO-9919327-A1
优先权日:1997-10-14
标题 :Process for the synthesis of chloropurine intermediates

专利号:EP-1023292-B1
优先权日:1997-10-14
标 题:Process for the synthesis of chloropurine intermediates