专利号:US-8471023-B2 优先权日:2009-06-11 标 题:Reductive amination of 6-keto normorphinans by catalytic hydrogen transfer 发明人:GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W 权利人:GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W; MALLINCKRODT LLC 摘要:The present invention provides processes for the stereoselective synthesis of 6-alpha-amino morphinans. In particular, the invention provides processes for the reductive amination of 6-keto normorphinans by catalytic transfer hydrogenation.
专利号:US-4436835-A 优先权日:1982-03-24 标 题:Process for preparation of catalysts 发明人:HORIE SHIGERU; YAMAMOTO YASUO; IKARASHI TAKEO 权利人:MITSUBISHI GAS CHEMICAL CO 摘要:Disclosed is a process for the preparation of a catalyst for the synthesis of methyl formate by dehydrogenating methanol in the gaseous phase, said process being characterized in that (A) at least one phosphate selected from the group consisting of copper phosphates, zinc phosphates and aluminum phosphates, and (B) at least one chloride selected from the group consisting of copper chlorides, zinc chloride, aluminum chloride, alkali metal chlorides and alkaline earth metal chlorides and/or (C) at least one compound selected from the group consisting of alkali metal compounds (exclusive of halides) and alkaline earth metal compounds (exclusive of halides) are added to copper oxide, zinc oxide and aluminum oxide. The catalyst obtained according to this process has a high activity for preparing methyl formate by dehydrogenating methanol in the gaseous phase, and this catalyst is excellent in the heat resistance and durability and has a high mechanical strength.
专利号:US-10300471-B2 优先权日:2013-10-08 标题 :Ruthenium-catalyzed synthesis of biaryl compounds in water 发明人:KOOHANG ALI AIDEN; MEHTA ANITA 权利人:CHICAGO DISCOVERY SOLUTIONS LLC 摘要:Using a [RuCl 2 (arene)] 2 complex and a formate source, a directed ortho C—H insertion and aryl-aryl coupling sequence in water provides biaryl compounds useful in the preparation of biologically active molecules and intermediates. Reactions may be conducted in the ambient atmosphere. Ruthenium catalysts prepared from [RuCl 2 (arene)] 2 and a formate source may be prepared in situ or isolated for later use.
专利号:US-8415474-B2 优先权日:2009-09-24 标题 :One-pot preparation of hexahydroisoquinolines from dihydroisoquinolines 发明人:GROTE CHRISTOPHER W; MOSER FRANK W; WANG PETER X; CANTRELL GARY L; BERBERICH DAVID W 权利人:GROTE CHRISTOPHER W; MOSER FRANK W; WANG PETER X; CANTRELL GARY L; BERBERICH DAVID W; MALLINCKRODT LLC 摘要:The present invention provides an efficient process for the preparation of hexahydroisoquinolines from dihydroisoquinolines. In particular, the invention provides a good yielding, one-pot process for the synthesis of hexahydroisoquinolines.
专利号:US-8519133-B2 优先权日:2009-06-11 标 题 :Preparation of 6-alpha-amino N-substituted morphinans by catalytic hydrogen transfer 发明人:GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W 权利人:GROTE CHRISTOPHER W; CANTRELL GARY L; MCCLURG JOSEPH P; THOMASSON CATHERINE E; MOSER FRANK W; MALLINCKRODT LLC 摘要:The present invention provides processes for the stereoselective synthesis of 6-alpha-amino N-substituted morphinans. In particular, the invention provides processes for the reductive amination of 6-keto N-substituted morphinans by catalytic hydrogen transfer.
专利号:US-3816473-A 优先权日:1971-11-08 标 题:Synthesis of 2,3-dihydro-2,2-dimethyl-7-benzofuranyl n-methyl-carbamate 发明人:SERBAN A; ENGEL P 权利人:ICI AUSTRALIA LTD 摘要:A PROCESS FOR THE PREPARATION OF CARBORFURAN WHICH PROCESS COMPRISES CONVERTING A-ISOPROPYPHENOL TO 2,3-DIHYDRO-2,2-DIMETHYL-7-ISOPROPYLBENZOFURAN (I); REACTING (I) WITH AN OXYGEN CONTAINING GAS TO FORM 2-(2,3-DIHYDRO2,2-DIMETHYL-7-BENZOFURANYL)-ISOPROPYL HYDROPEROXIDE (II); CATALYTICALLY DECOMPOSING (II) TO FORM 2,3-DIHYDRO2,2-DIMETHYL-7-HYDROXYBENZOFURAN (III); REACTING (III) WITH METHYL ISOCYANATE TO FORM 2,3-DIHYDRO-2,2-DIMETHYL7-BENZOFURANYL N-METHYLCARBAMATE (CARBOFURAN) AND RECOVERING SAID CARBAMATE. NEW COMPOUNDS USEFUL AS INTERMEDIATES IN THE ABOVE PROCESS ARE ALSO DESCRIBED.
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合成参考文献
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