CAS: 528521-87-1; (R)-(1,2',3,3'-Tetrahydro-1,2'-Spirobi[indene]-4,7'-Diyl)Bis(Di-P-Tolylphosphine)

该化合物是一个复杂的有机磷化合物,其特征是独特的脊柱膜结构.该化合物有两双(4-甲基苯基)光学组,有助于其在催化和材料科学中的潜在应用.斯皮罗本丁内细胞的存在具有僵硬性和持久性,影响其与其他化学物种的再活性和互动.已知磷化合物具有作为协调化学的木条和相互作用的能力,便利了金属化合物的形成.此外,该化合物的气质性(1R)配置表明,该化合物可能表现出特定的光学特性,这与不对称合成有关.

英文名称(R)-(1,2',3,3'-Tetrahydro-1,2'-Spirobi[indene]-4,7'-Diyl)Bis(Di-P-Tolylphosphine)
中文名称(R)-7,7'-双(二(对甲基苯基)膦基]-1,1'-螺二氢茚
IUPAC名称(1',2,3,3'-tetrahydro-1,2'-spirobi[indene]-4',7-diyl)bis(di-p-tolylphosphane)
CAS编号528521-87-1
MFCD编号:MFCD08459345
分子式:C45H42P2分子量:644.78
产品CID: 1515208
产品分类化学试剂 → 有机试剂 → 膦配体

相似结构搜索
InChIKey: VLIOMJFCGWZUON-UHFFFAOYSA-N
InChI=1S/C45H42P2/c1-31-11-19-37(20-12-31)46(38-21-13-32(2)14-22-38)42-9-6-8-36-29-45(30-41(36)42)28-27-35-7-5-10-43(44(35)45)47(39-23-15-33(3)16-24-39)40-25-17-34(4)18-2
计算化学: 氢键受体数*氢键供体数0.0可旋转键数6.0

MSDS等安全信息

警示词Warning
危险描述H302-H315-H319-H335-
防范说明P261-P305+P351+P338-
UN编号NONH for all modes of transport
危险品标志Xi

合成工艺路线路线简述

📜双(对甲基苯基)氧化膦置于palladium Diacetate,三氯硅烷,N,N-二异丙基乙胺,1,4-双(二苯基膦)丁烷体系中,用二甲基亚砜,甲苯作为反应溶剂,化学反应生成 (R)-7,7'-双(二(对甲基苯基)膦基]-1,1'-螺二氢茚
参考文献:Synthesis Of Spiro Diphosphines And Their Application In Asymmetric Hydrogenation Of Ketones
标题:Synthesis Of Spiro Diphosphines And Their Application In Asymmetric Hydrogenation Of Ketones
摘要:Synthesis Of Chiral Diphosphine Ligands Containing A Spiro Scaffold Was Described. The Ruthenium Complexes Of These Spiro Ligands Were Found To Have Extremely High Activities (S/c Up To 100 000) And Enantioselectivities (Ee Up To 99.5%) In The Asymmetric Hydrogenation Of Aromatic,Heteroaromatic,And Alpha,Beta-Unsaturated Ketones.
DOI:10.1021/ja029907I