专利号:US-10870649-B2 优先权日:2017-04-13 标题:Synthesis of NIR fluorescent probe 发明人:LATTUADA LUCIANO; BUONSANTI FEDERICA; CRIVELLIN FEDERICO; FERRETTI FULVIO; MAISANO FEDERICO; ORIO LAURA; PIZZUTO LORENA 权利人:BRACCO IMAGING SPA 摘要:The application relates to a process for the synthesis of a Near Infra-Red (NIR) fluorescent probe which is a cRGD-Cy5.5 conjugate of formula (I) known as DA364 comprising an aza-bicycloalkane based cyclic peptide labelled with a Cy5.5 dye moiety and used in the guided surgery of tumors and pathologic regions.
专利号:US-2020055855-A1 优先权日:2017-04-13 标题 :Improved synthesis of nir fluorescent probe
专利号:CN-110461843-B 优先权日:2017-04-13 标题:Improved synthesis of NIR fluorescent probes
专利号:EP-3609892-B1 优先权日:2017-04-13 标 题:Improved synthesis of nir fluorescent probe
参考文献:10.1007/s10870-005-9063-3 摘要:Downer SM, Squattrito PJ, Bestaoui N, Clearfield A. Structures of transition and alkaline earth metal salts of 5-aminonaphthalene-2-sulfonate and 6-aminonaphthalene-1, 3-disulfonate: Some unusual coordination behaviors. Journal of Chemical Crystallography. 2006 Jun 07;36(8):487–501. doi: 10.1007/s10870-005-9063-3.