CAS: 23244-49-7; Pentaethylene Glycol Monodecyl Ether

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3055-99-0 19327-39-0 5274-63-5

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oxirane 1-Decanol

📜环氧乙烷,癸醇置于k10 Clay体系中,用95%的收率获得五聚乙二醇单癸醚
参考文献:非离子型isatin表面活性剂:合成,量子化学计算,Admet及其抗菌活性
标题:非离子型isatin表面活性剂:合成,量子化学计算,Admet及其抗菌活性
摘要:建立表面活性分子的最大挑战是通过非常好的生物活性最大化其表面活性.非离子表面活性剂(n-Isatin-Eo M-C N,其中m为5,7和9乙二醇单元,N为8,10和12),是通过首先使isatin与氯乙酸反应,然后与不同类型的乙氧基化(具有8,7和9个环氧乙烷单元的c 8-c 12)脂肪醇.Ftir和1表征了所制备的表面活性剂. 1 H NMR确认结构.评价了表面活性剂的表面活性,生物降解性,抗微生物性和抗真菌活性.另外,进行了量子化学计算和口服生物利用度计算.所得数据表明,所有合成的化合物均具有非常好的表面活性,生物降解性和生物活性.
Doi:10.1002/jsde.12379

专利信息

专利号:US-2012190064-A1
优先权日:2004-10-01
标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
发明人：KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA
权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP
摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.

专利号:US-11618777-B2
优先权日:2015-07-31
标 题 :Method of manufacturing membrane protein and utilization thereof
发明人：YOKOYAMA SHIGEYUKI; SHINODA TAKEHIRO; ITO KAORI; NOMURA NAOKO; KATSURA YOSHIKO; SOMEYA TOMOMI; SHIROUZU MIKAKO; HORI TETSUYA; NAKAMURA YOSHIHIRO; TANABE HIROAKI
权利人:YOKOYAMA SHIGEYUKI
摘要:In order to provide a membrane protein production method which does not require the step of solubilizing a membrane protein and which allows the membrane protein having an excellent quality to be obtained with a high yield, a method in accordance with an embodiment of the present invention includes: a step (a) of preparing a reaction solution for cell-free protein synthesis, the reaction solution containing (i) a template nucleic acid which encodes the membrane protein, (ii) a lipid, and (iii) a detergent which is contained at a concentration equal to or higher than a critical micelle concentration; and a step (b) of synthesizing the membrane protein while the concentration of the detergent in the reaction solution is maintained at a concentration equal to or higher than a critical micelle concentration.

专利号:US-2009209032-A1
优先权日:2004-10-01
标 题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules

专利号:EP-1848812-A2
优先权日:2004-10-01
标题:Feeding buffers, systems, and methods for in vitro synthesis of biomolecules

专利号:US-2006110788-A1
优先权日:2004-10-01
标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules

专利号:WO-2006039622-A2
优先权日:2004-10-01
标 题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules