CAS: 182344-29-2; (4'-Ethoxy-[1,1'-Biphenyl]-4-yl)Boronic Acid

该化合物是一种有机有机体化合物,其特征是存在一种含有乙氧替代物的联苯结构的碱酸功能组,该化合物通常具有以下特性:白对白固体,可溶于乙醇和二氯甲烷等有机溶剂,但因其氢恐惧性双苯核心而在水中较不易溶.已知乙氧基酸组有能力与二醇形成可逆共价联系,使其在各种应用中有用,包括有机合成,医药化学和材料科学.它可以参与铃木-米亚乌拉的交叉组合反应,这些反应对于构建复杂的有机分子至关重要.此外,乙氧组可影响化合物的再活性和溶性,增强其在多种化学过程中的效用.

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CAS号58743-80-9 1-(4-Bromopheny... | CAS号148-86-7 4-乙酰氧基联苯 | CAS号92-69-3 4-苯基苯酚 | CAS号29558-77-8 4-羟基-4'-溴联苯 | CAS号84244-98-4 4-乙酰氧基-4'-溴代联苯

合成工艺路线路线简述

    📜1-溴-4-(4-乙氧基苯基)苯置于正丁基锂,硼酸三甲酯,盐酸体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应生成4-乙氧基二苯基-4-硼酸
    参考文献:The Synthesis And Property Of Liquid Crystalline 4-Alkoxyl-4″-Cyano-P-Terphenyls
    标题:The Synthesis And Property Of Liquid Crystalline 4-Alkoxyl-4″-Cyano-P-Terphenyls
    摘要:The Synthesis Of Some New 4-Alkoxyl-4 "-Cyano-P-Terphenyls Is Described. The Preliminary Characterization By Means Of Polarized Optical Microscopy,Differential Scanning Calorimetry And X-Ray Diffraction Shows That All These Compounds Are Thermotropically Liquid-Crystalline And Can Form Both The Nematic And Smectic Mesophases.
    Doi:10.1080/10587250008031039

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    专利信息


    专利号:US-10202374-B2
    优先权日:2014-02-27
    标题 :6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors
    发明人:VISHWAKARMA RAM ASREY; BHARATE SANDIP BIBISHAN; BHUSHAN SHASHI; YADAV RAMMOHAN RAO; GURU SANTOSH KUMAR; JOSHI PRASHANT
    权利人:COUNCIL SCIENT IND RES
    摘要:The present invention relates to 6-aryl-4-phenylamino quinazolines of formula I wherein, R and R′ are as herein described. The present invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-α (PI3K-α) inhibitory activity. In addition, the invention relates to methods of using compounds for treating or preventing various cancers such as pancreatic, prostate, breast and melanoma.

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    合成参考文献


    摘要:Kleemann A., Kutscher B., Reichert D., Bossart M., Pharmaceutical Substances, Thieme [Online], Stuttgart, (2025).
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