CAS: 1546-78-7; 4-Hydroxy-6-(Trifluoromethyl)Pyrimidine

相似化合物

126538-89-4 2836-44-4 672-45-7

上下游产品

CAS号368-54-7 4-羟基-6-(三氟甲基)嘧啶-2-硫醇 | CAS号37552-81-1 4-氯-6-三氟甲基嘧啶 | CAS号672-41-3 4-氨基-6-三氟甲基嘧啶 | CAS号220880-12-6 4-三氟甲基嘧啶-5-甲酸 | CAS号785777-94-8 4,5-二溴-6-三氟甲基嘧啶 | CAS号785777-95-9 5-溴-4-肼基-6-三氟甲基嘧啶

4-羟基-6-(三氟甲基)嘧啶-2-硫醇置于双氧水体系中,用 四氢呋喃,水 用作溶剂,化学反应 2.0H,以70%的收率获得4-羟基-6-三氟甲基嘧啶
参考文献:溴化 4-(三氟甲基)嘧啶:方便获取多功能中间体
标题:溴化 4-(三氟甲基)嘧啶:方便获取多功能中间体
摘要:在整篇论文中,错误的试剂名称"三溴化磷"和"三氯化磷"应替换为正确的名称"三溴化磷"(Pobr3) 和"三氯化磷"(Pocl3).[on Scifinder (R)]
Doi:10.1002/ejoc.200400209

专利信息

专利号:US-7754188-B2
优先权日:2003-06-30
标 题:Radiolabeled cannabinoid-1 receptor modulators
发明人：BURNS H DONALD; CHEN ALEX M; GIBSON RAYMOND E; GOULET MARK T; HAGMANN WILLIAM K; HAMILL TERENCE G; JEWELL JAMES P; LIN LINUS S; LIU PING; PERESYPKIN ANDREY V
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.