CAS: 132-13-8; (2S,3R,4S,5R)-2-(5,6-Dimethyl-1H-Benzo[d]Imidazol-1-yl)-5-(Hydroxymethyl)Tetrahydrofuran-3,4-Diol

上下游产品

1-(2,3-O-Isopropylidene-5-O-Triphenylmethyl-α-D-Ribofuranosyl)-5,6-Dimethylbenzimidazole 84396-42-9
1-(5-O-Triphenylmethyl-2,3-O-Isopropylidene-β-D-Ribofuranosyl)-5,6-Dimethylbenzimidazole 84396-43-0

📜5-O-三苯甲基-2,3-O-异亚丙基-D-呋喃核糖置于2-Fluoro-Methylpyridinium Tosylate,四溴化碳,N,N-二异丙基乙胺体系中,用 甲醇,二氯甲烷 用作溶剂,化学反应 12.0H,反应生成(2S,3R,4S,5R)-2-(5,6-二甲基苯并咪唑-1-基)-5-(羟基甲基)四氢呋喃-3,4-二醇
参考文献:Deprotection Of α-Imidazole/benzimidazole Ribonucleosides By Catalytic Carbon Tetrabromide Initiated Photolysis
标题:Deprotection Of α-Imidazole/benzimidazole Ribonucleosides By Catalytic Carbon Tetrabromide Initiated Photolysis
摘要:Several Protected Benzimidazole And Imidazole Alpha-Ribonucleosides Were Deprotected In Excellent Yield Lit Ambient Temperature Using Cbr4 Initiated Photolysis In Methanol At Ambient Temperature. No Selectivity Was Observed And Both Trityl And Isopropylidene Groups Were Deprotected Under The Reaction Conditions. (C) 2005 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2005.09.180

专利信息

专利号:US-2011296543-A1
优先权日:2006-06-01
标题:Nucleic acids and proteins and methods for making and using them
发明人：CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON
权利人:CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON; UNIV CALIFORNIA; CALIFORNIA INST OF TECHN; VERENIUM CORP
摘要:The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.