CAS: 13168-24-6; 3-O-(-D-Galactopyranosyl)-D-Galactose

专利信息

专利号:US-2004058888-A1
优先权日:2000-01-13
标题:Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides
发明人：BORNAGHI LAURENT; DEKANY GYULA; DRINNAN NICHOLAS BARRY; PAPAGEORGIOU JOHN; WEST MICHAEL LEO
摘要:This invention relates to reagents and methods for synthesis of biologically active di- and tri-saccharides comprising α-D-Gal(1→3)-D-Gal. In particular the invention provides novel reagents, intermediates and processes for the solution or solid phase synthesis of α-D-galactopyranosyl-(1→3)-D-galactose, and derivatives thereof. In one preferred embodiments the invention provides a protected monosaccharide building block of general formula (II): in which R 3 is methoxy or methyl; R 1 is H, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl; and R 2 is H, Fmoc, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4 -chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl.

专利号:US-2002132320-A1
优先权日:2001-01-10
标题:Glycoconjugate synthesis using a pathway-engineered organism
发明人：WANG PENG GEORGE; CHEN XI; LIU ZIYE; ZHANG WEI
摘要:This invention relates to methods and compositions for the production of glycoconjugates. In particular, organisms are provided with at least one heterologous gene encoding an enzyme for regenerating a sugar nucleotide along with at least one glycosyltransterase. Such organisms are useful for the large-scale synthesis of glycoconjugates.

专利号:EP-1257558-A1
优先权日:2000-01-13
标 题:Methods for synthesis of alpha-d-gal (1- 3) gal-containing oligosaccharides

专利号:US-2017016040-A1
优先权日:2011-07-21
标题:Chemoenzymatic synthesis of heparin and heparan sulfate analogs

专利号:US-10160986-B2
优先权日:2011-07-21
标 题 :Chemoenzymatic synthesis of heparin and heparan sulfate analogs

专利号:US-2017204444-A9
优先权日:2011-07-21
标题:Chemoenzymatic synthesis of heparin and heparan sulfate analogs