CAS: 920-42-3; Formic Acid-D2

上下游产品

CAS号2065-73-8 Oxalic Acid-d2 | CAS号3996-15-4 甲酸钠-D | CAS号14335-33-2 氘代磷酸 | CAS号143-33-9 氰化钠 | CAS号144-62-7 草酸 | CAS号64-18-6 甲酸 | CAS号811-98-3 氘代甲醇 | CAS号124-38-9 二氧化碳 | CAS号201230-82-2 carbon monoxide | CAS号7789-20-0 重水 | CAS号23731-38-6 氘代甲酸甲酯 | CAS号107-18-6 烯丙醇 | CAS号35434-71-0 trimethyl-d8-amine | CAS号13960-80-0 三甲基-d9-胺 | CAS号102910-30-5 丙烯醇-D5

氰化钠置于重水,氘代磷酸体系中,化学反应生成 甲酸-D2
参考文献:金属辅助反应.第16部分:1:通过氘标记进行非均相液相催化转移氢解反应机理的研究
标题:金属辅助反应.第16部分:1:通过氘标记进行非均相液相催化转移氢解反应机理的研究
摘要:氢同位素研究表明,液相中酚(1)的四唑基醚中co键的非均相催化转移氢解是通过将氢从活性氢供体中心直接转移到催化剂表面的醚上进行的,而不是通过氢的转移进行的催化剂表面的原子.
DOI:10.1016/s0040-4020(01)96645-1

专利信息

专利号:US-11708320-B2
优先权日:2018-06-29
标 题:Environmentally-friendly hydroazidation of olefins
发明人：XU HAO
权利人:UNIV GEORGIA STATE RES FOUND
摘要:The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.

专利号:WO-2025050002-A1
优先权日:2023-09-01
标题:Use of pyridoxatin and related analogs for control of candida auris
发明人：REPETTI PETER; PEARCE CEDRIC; RATCLIFFE OLIVER
权利人:REPETTI PETER P; PEARCE CEDRIC J; RATCLIFFE OLIVER J
摘要:Fungi are prolific producers of secondary metabolites and represent a rich and relatively untapped source for novel drug leads. Numerous successful therapeutics have derived from fungi, including penicillin, cephalosporin, statins, and cyclosporin. However, many promising classes of natural product are never developed into drugs because their chemical synthesis is complex or because the native organisms that naturally produce them, do so at impractically low levels. Pyridoxatins are a class of promising anti-fungal secondary metabolites produced by several naturally occurring strains filamentous fungi. The molecules have complex structures that impede straightforward chemical synthesis or analoging to increase efficacy. The disclosure herein details novel a novel use of pyridoxatin class molecules for the treatment of Candida auris and novel methods for the biosynthesis of pyridoxatins through fermentation of engineered microbes.

专利号:US-2023346952-A1
优先权日:2015-09-22
标题:Cannabinoid glycoside prodrugs and methods of synthesis
发明人：ZIPP BRANDON J; HARDMAN JANEE’ M; BROOKE ROBERT T; DEUTSCHER TYREL R
权利人:GRAPHIUM BIOSCIENCES INC
摘要:The present invention provides tetrahydrocannabinol glycoside and cannabidiol glycoside prodrugs and pharmaceutical compositions comprising these compounds, and their use for the site-specific delivery of tetrahydrocannabinol or cannabidiol. Also provided are processes for the preparation of purified tetrahydrocannabinol glycoside and cannabidiol glycoside prodrugs.

专利号:US-5132419-A
优先权日:1989-10-03
标题 :Process for the preparation of 7-amino-3-((z)-1-propen-1yl)-3-cephem-4-carboxylic acid
发明人：LANZ JOACHIM; NAAB PAUL; ROSENTRETER ULRICH
权利人:BAYER AG
摘要:(7-APCA) having the formula (I) ##STR1## which is an important synthesis intermediate in the preparation of cephalosporin-like antibiotics, is prepared by treating a compound of the formula (II) ##STR2## in which R 1 and R 2 represent alkyl, aryl and aralkyl radicals, with a strong protonic acid or with a Lewis acid. Compound (II) is prepared by adding triphenylphosphine and alkali metal iodide to a compound of the formula (VI) ##STR3## then reacting with acetaldehyde in base. Compound (VI) is prepared by treating a compound of the formula (VII) ##STR4## with a base in a polar solvent at -70° C. to 0° C. Compound (VII) is prepared by treating a compound of the formula (VIII) ##STR5## with a chlorinating agent in an organic solvent.

专利号:WO-2024219698-A1
优先权日:2023-04-19
标 题 :Composition for preventing, ameliorating, or treating arthritis, containing potentilla chinensis extract or apigenin-7-o-glucuronide as active ingredient
发明人：JUNG BYUNG CHAN; LEE SUN HEE; LEE KYUNG-TAE; LEE SANG OK; SHIN DONG MIN
权利人:BELABELBIO INC
摘要:The present invention discloses a composition for preventing, ameliorating, or treating arthritis, the composition containing a Potentilla chinensis extract or apigenin-7-O-glucuronide as an active ingredient. The present invention inhibits the expression of MMP-1 and MMP-9, increases the synthesis of procollagen type 2, and not only alleviates inflammation but also inhibits inflammatory pain, and thus has the effect of preventing, ameliorating, or treating arthritis.

专利号:WO-2025125811-A1
优先权日:2023-12-12
标题:Heterocyclic compounds and their use for the treatment of neurological disorders
发明人：PLOWRIGHT ALLEYN THOMAS; PFEIFFER THOMAS; MÄRCHER-RØRSTED EMIL; DUCKWORTH EDWARD JOSEPH
权利人:ONTRACK THERAPEUTICS LTD
摘要:The present invention relates to novel synthetic compounds of Formula (I) and (II) related to naturally occurring flavonoids such as 7,8-dihydroxyflavone (7,8-DHF). The invention further relates to the method of synthesis, the use of these compounds as research tools and their use as pharmaceuticals.