CAS: 83585-56-2; 2-Aminomethyl-15-Crown-5

该化合物是一个化学复合体,其独特结构包括五氧环戊开丙烷的脊椎.该结构有五醚联系,有助于极地溶剂中的潜在溶性及其形成氢结的能力.甲胺功能组的存在具有基本性和潜在反应性,允许其参与各种化学反应,包括以地雷为基础的核分裂哲学替代.该化合物可能具有低挥发性和高热稳定性等特性,因为其分子规模巨大,而且存在乙醚联系.其应用可能跨越材料科学,制药和表面活性剂等领域,而其独特的结构特征可能提供具体的功能.此外,该化合物的安全性和处理需要与任何化学品一起加以评估,以确保其在实验室或工业环境中的适当使用.

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相似化合物

1523541-84-5 1523541-96-9 1185156-19-7

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合成工艺路线路线简述

  • 19249-03-7 + 344242-14-4 = 83585-56-2
    反应条件:1.1 Catalysts: Sodium Tert-Butoxide
    标题:Synthesis Of Aminomethyl Crown Ethers
    作者:Maeda,Hirokazu; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1982 卷标:47(26) 页码:5167-71]

    15045-14-4 = 83585-56-2
    反应条件:1.1 Reagents: Ammonia Catalysts: Sodium Carbonate2.1 Catalysts: Sodium Tert-Butoxide
    标题:Synthesis Of Aminomethyl Crown Ethers
    作者:Maeda,Hirokazu; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1982 卷标:47(26) 页码:5167-71]

    75-21-8 = 83585-56-2
    反应条件:1.1 Reagents: Boron Trifluoride Solvents: Diethyl Ether2.1 Reagents: Ammonia Catalysts: Sodium Carbonate3.1 Catalysts: Sodium Tert-Butoxide
    标题:Synthesis Of Aminomethyl Crown Ethers
    作者:Maeda,Hirokazu; Et Al
    参考文献:Journal Of Organic Chemistry 日期:1982 卷标:47(26) 页码:5167-71
📜2-[3-Chloro-2-(2-Hydroxyethoxy)Propoxy]Ethanol置于ammonium Hydroxide,Potassium Carbonate,Sodium T-Butanolate体系中,化学反应 55.0H,反应生成 2-氨基甲基-15-冠-5
参考文献:Synthesis Of Aminomethyl Crown Ethers
标题:Synthesis Of Aminomethyl Crown Ethers
摘要:
DOI:10.1021/jo00147A025

海关参考信息

专利信息


专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人:SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:CN-104470547-B
优先权日:2012-05-24
标题 :Utilize the method for tubular article synthesis of radiopharmaceuticals

专利号:US-9550704-B2
优先权日:2012-05-24
标 题 :Method for synthesizing radiopharmaceuticals using a cartridge
发明人:CHI DAE YOON; LEE BYOUNG SE; LEE JAE HAK; CHU SO YOUNG; JUNG WOON JUNG
权利人:FUTURECHEM CO LTD
摘要:The present invention relates to a method for synthesizing a radiopharmaceutical using a cartridge, which makes it possible to carry out several steps of reaction required for synthesizing a radiopharmaceutical in the cartridge filled with a polymer. A method for synthesizing a radiopharmaceutical according to the present invention enables each step's reaction to be carried out with the solution confined in the cartridge so as not to flow out, thus being simplified compared to the conventional methods for synthesizing radiopharmaceuticals, and expediting the synthesis thereof.

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合成参考文献


参考文献:10.1055/s-2006-944230
摘要:Chang S, Huang Z, Kim S. Synthesis, Characterization, and Binding Properties of Novel Penta-Crown Ethers. Synlett. 2006 Jul;2006(11):1707–10. doi: 10.1055/s-2006-944230.
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