CAS: 67622-86-0; 2-Methyl-1-(Methylamino)Propan-2-Ol

相似化合物

183059-24-7 80466-51-9 79365-81-4

上下游产品

formaldehyd 2-hydroxy-2-methylpropanenitrile 3-chloro-2-methylpropan-2-ol methylamine methyl-(2-methyl-2-phenyl-propyl)-amine

📜1-氯-2-甲基-2-丙醇,甲胺置于水体系中,化学反应生成 2-甲基-1-甲基氨基-丙烷-2-醇
参考文献:Preparation Of Aminobenzoic Acid Esters Of Substituted Monoalkylamino Alcohols
标题:Preparation Of Aminobenzoic Acid Esters Of Substituted Monoalkylamino Alcohols
摘要:
DOI:10.1021/ja01267A100

专利信息

专利号:US-7772246-B2
优先权日:2007-08-01
标题:Pyrazole compounds as RAF inhibitors
发明人：CUI JINGRONG JEAN; DEAL JUDITH GAIL; GU DANLIN; GUO CHUANGXING; JOHNSON MARY CATHERINE; KANIA ROBERT STEVEN; KEPHART SUSAN ELIZABETH; LINTON MARIA ANGELICA; MCALPINE INDRAWAN JAMES; PAIRISH MASON ALAN; PALMER CYNTHIA LOUISE
权利人:PFIZER
摘要:The present invention is directed to compounds of Formula (I), n nand to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.

专利号:US-9957277-B2
优先权日:2015-11-25
标题 :eIF4A-inhibiting compounds and methods related thereto
发明人：ERNST JUSTIN T; REICH SIEGFRIED H; SPRENGELER PAUL A; TRAN CHINH VIET; PACKARD Garrick Kenneth; XIANG ALAN X; NILEWSKI CHRISTIAN; MICHELS THEO
权利人:EFFECTOR THERAPEUTICS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. n nFor Formula I compounds X, Y, R 1 , R 2 , R 3a , R 3b , R 4a , R 4b and R 5 are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4A and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.