CAS: 33252-30-1; 2-Chloroisonicotinonitrile

相似化合物

101066-61-9 6313-54-8 100859-84-5

上下游产品

CAS号14906-59-3 4-氰基吡啶 n-氧化物 | CAS号7440-44-0 活性炭 | CAS号10026-13-8 五氯化磷 | CAS号38557-82-3 Isonicotinamide... | CAS号2402-95-1 2-氯吡啶-N-氧化物 | CAS号14432-16-7 2-氯-4-硝基吡啶氮氧化物 | CAS号1453-82-3 异烟碱 | CAS号14432-12-3 4-氨基-2-氯吡啶 | CAS号151-50-8 氰化钾 | CAS号10025-87-3 三氯氧磷 | CAS号3939-14-8 4-氰基-2-氟吡啶 | CAS号33744-17-1 2-苯基异烟腈 | CAS号42182-27-4 2-氨基-4-氰基吡啶 | CAS号219832-71-0 4-(2-ethyl-1,3-... | CAS号82019-89-4 2-氯乙酸异烟酰胺 | CAS号857653-85-1 氯羟基异烟碱 | CAS号6313-54-8 2-氯异烟酸 | CAS号72716-86-0 4-氰基-2-甲氧基砒啶 | CAS号72716-87-1 2-甲氧基-4-吡啶甲醛 | CAS号127680-91-5 2-吗啉异烟腈

2-氯吡啶-N-氧化物置于硫酸,硝酸,铁粉,Copper(II) Sulfate,溶剂黄146,Sodium Nitrite体系中,化学反应生成2-氯-4-氰基吡啶
参考文献:Talik; Plazek,Roczniki Chemii,1955,Vol. 29,P. 1019,1025
标题:Talik; Plazek,Roczniki Chemii,1955,Vol. 29,P. 1019,1025

专利信息

专利号:US-2025129021-A1
优先权日:2023-09-19
标 题:Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I), Formula (V)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-3919155-A
优先权日:1970-12-18
标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人：SQUIRE EDWARD NOONAN
权利人:DU PONT
摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres and in the presence of from 1 mole percent to 250 mole percent of water based on the molar amount of the aromatic compound.

专利号:US-4031106-A
优先权日:1973-12-19
标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人：DELPESCO THOMAS WAYNE
权利人:DU PONT
摘要:An improved process is provided for producing an aromatic amine from ammonia and an aromatic compound which comprises reacting the aromatic compound with ammonia at a temperature of from about 150 DEG C. to about 500 DEG C. and at a pressure of from about 10 to about 1000 atmospheres in the presence of a conditioned nickel/nickel oxide/zirconium oxide cataloreactant containing an oxide of lanthanum, samarium, holmium, europium, erbium, yttrium, praseodymium, neodymium, terbium, ytterbium, dysprosium or a mixture of any of them.

专利号:US-4001260-A
优先权日:1973-12-19
标 题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人：DEL PESCO THOMAS W
权利人:DU PONT
摘要:An improved process is provided for producing an aromatic amine from ammonia and an aromatic compound which comprises reacting the aromatic compound with ammonia at a temperature of from about 150° C. to about 500° C. and at a pressure of from about 10 to about 1000 atmospheres in the presence of a conditioned nickel/nickel oxide/zirconium oxide cataloreactant which has been treated with ammonia prior to introduction of the cataloreactant to the amination reactants.

专利号:US-2003055255-A1
优先权日:2001-06-20
标 题 :Synthesis of substituted imidazoles
发明人：MARCANTONIO KAREN; FREY Lisa; FRANTZ DOUG; MURRY JERRY A; TILLYER RICHARD
摘要:The present invention prepares imidazoles by the selective closure of a keto-amide to form the imidazolyl ring. In particular, the present invention selectively closes a keto-amide substituted with three rings to form a tri-substituted imidazole.

专利号:US-11739065-B2
优先权日:2016-06-13
标题 :FXR (NR1H4) modulating compounds
发明人：BLOMGREN PETER A; CURRIE KEVIN S; GEGE CHRISTIAN; KROPF JEFFREY E; XU JIANJUN
权利人:GILEAD SCIENCES INC
摘要:The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.