CAS: 2675-89-0; 2-Chloro-N,N-Dimethylacetamide

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CAS号506-59-2 盐酸二甲胺 | CAS号79-04-9 氯乙酰氯 | CAS号124-40-3 二甲胺 | CAS号74-89-5 氨基甲烷 | CAS号463-51-4 乙烯酮 | CAS号1585-74-6 CHLORODIMETHYLAMINE | CAS号79-11-8 氯乙酸 | CAS号51-80-9 四甲基甲烷二胺 | CAS号541-88-8 氯乙酸酐 | CAS号139575-17-0 2-(dimethylamin... | CAS号106231-54-3 [2-(dimethylami... | CAS号2279-84-7 2-diethoxyphosp... | CAS号28755-03-5 2-氯-1-(1H-吲哚-3-基)-乙酮 | CAS号24011-73-2 N,N-dimethyl-2-... | CAS号23694-02-2 2-氯-1-(1-甲基-1H-... | CAS号126624-55-3 2-氯-1-(1-甲基-1H-... | CAS号10397-59-8 N,N-dimethyl-2-... | CAS号30515-58-3 4-Pyridinecarbo... | CAS号358780-16-2 Ethanone, 2-chl... | CAS号13574-14-6 Acetamide,2-(di...

N,N-二甲基乙酰胺置于copper Dichloride体系中,化学反应 24.0H,反应生成2-氯-N,N-二甲基乙酰胺
参考文献:Cu(II)-Mediated Keto C(Sp3)-h Bond α-Acyloxylation Of N,N-Dialkylamides With Aromatic Carboxylic Acids
标题:Cu(II)-Mediated Keto C(Sp3)-h Bond α-Acyloxylation Of N,N-Dialkylamides With Aromatic Carboxylic Acids
摘要:铜(II)催化的芳香羧酸与n,N-二烷基酰胺的酮基邻位c(Sp3)-h键的氧化偶联的第一个例子已经被开发出来.
Doi:10.1039/c7Ob01190C

专利信息

专利号:US-9388147-B2
优先权日:2009-11-13
标题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TIMONY GREGG ALAN; BROOKS JENNIFER L; PEACH ROBERT; SCOTT FIONA LORRAINE; HANSON MICHAEL ALLEN
权利人:RECEPTOS INC; CELGENE INTERNAT II SÃ RL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-2004171072-A1
优先权日:1998-03-31
标题:Solid support based on selenium useful in solid phase synthesis
发明人：RUHLAND THOMAS; ANDERSEN KIM; PEDERSEN HENRIK
权利人:LUNDBECK & CO AS H
摘要:This invention relates to novel solid support based on selenium and a method for the preparation thereof. The solid support is useful in solid phase synthesis of organic compounds including combinatorial libraries of compounds.

专利号:US-9394264-B2
优先权日:2009-11-13
标 题:Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA
权利人:RECEPTOS INC
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-4921955-A
优先权日:1987-11-06
标 题 :Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives
发明人：TOEPFL WERNER
权利人:CIBA GEIGY CORP
摘要:The invention relates to a process for the preparation of 1,5-disubstituted imidazoles of the formula (I) by alkylation of an N-cyanoformamidine of the formula II X-NH-CH=N-CH (II) to form an N,N-disubstituted N'-cyanoformamidine of the formula (IV) which is cyclised under the action of bases to form a 4-aminoimidazole of the formula (V) and then reduced to form the product of the formula I. The invention relates also to a special process for the reduction of the aminoimidazole V to I, and to intermediate compounds for carrying out this process and to processes for the preparation of the intermediate compounds. The meaning of the substituents X and L is explained in detail in the text.

专利号:US-2006167268-A1
优先权日:2002-04-09
标 题:Growth hormone secretagogues
发明人：EVERS BRITTA; GERD RUEHTER; MARTIN DE LA NAVA EVA M; TEBBE MARK J
权利人:ELI LILLY AND COMPANY PATENT D
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.

专利号:US-2024390383-A1
优先权日:2021-09-28
标题 :Dioxazines and their use in treatment of gba-related diseases
发明人：NEVE SØREN; BROWN WILLIAM DALBY; THIRSTRUP KENNETH
权利人:ZEVRA DENMARK AS
摘要:The present invention relates to dioxazines, their synthesis, and their use for increasing GBA activity and/or levels as well as treatment of GBA-related diseases, such as Parkinson's disease.