CAS: 26575-95-1; (1S,3R)-1-((R)-3,3-Dimethyloxiran-2-yl)-3-((5R,8S,9S,10S,11S,14R)-11-Hydroxy-4,4,8,10,14-Pentamethyl-3-Oxo-2,3,4,5,6,7,8,9,10,11,12,14,15,16-Tetradecahydro-1H-Cyclopenta[a]Phenanthren-17-yl)Butyl

专利信息

专利号:US-2023391818-A1
优先权日:2020-11-05
标 题:Peptide synthesis method for suppressing defect caused by diketopiperazine formation
发明人：NOMURA KENICHI; KAGE MIRAI; TAMIYA MINORU; KANAZAWA JUNICHIRO
权利人:CHUGAI PHARMACEUTICAL CO LTD
摘要:Solid-phase synthesis of a peptide has a problem that a desired elongation reaction is prevented from proceeding by diketopiperazine and a 6-membered diamine skeleton compound formed when a protective group at the N-terminal is removed. The present inventors have found that when in production of a peptide by a solid-phase method, a peptide in which an amino group at the N-terminal is protected with a protective group having an Fmoc skeleton is treated in a specific solvent with a base having a pKa of 23 or more in acetonitrile as a conjugate acid, and a peptide chain is then elongated, it is possible to solve the problem described above.

专利号:US-2022162188-A1
优先权日:2019-01-15
标 题:Isoprenoids and methods of making thereof
发明人：WILLIAMS GAVIN; LUND SEAN; HALL RACHAEL
权利人:UNIV NORTH CAROLINA STATE
摘要:Disclosed are methods for preparing isoprenoid subunits, as well as methods of employing these isoprenoid subunits for the synthesis of isoprenoids. Also provided are isoprenoids prepared using the methods described herein.

专利号:US-2024335497-A1
优先权日:2021-07-26
标题 :Pulse protein-based composition for activating the synthesis of fgf19

专利号:EP-4376865-A2
优先权日:2021-07-26
标题 :Pulse protein-based composition for activating the synthesis of fgf19

专利号:WO-2023006248-A2
优先权日:2021-07-26
标 题 :Method for activating the synthesis of fgf19

专利号:RU-2124009-C1
优先权日:1992-01-21
标题 :Derivatives of 1,5-benzodiazepine, method of their synthesis, pharmaceutical composition