CAS: 25940-35-6; Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid

相似化合物

115932-00-8 25939-87-1 869941-96-8

上下游产品

CAS号937602-40-9 吡唑并[1,5-a]嘧啶-3-羰酰氯

Methyl Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate置于水,Sodium Hydroxide体系中,用 甲醇 用作溶剂,化学反应生成吡唑并[1,5-A]嘧啶-3-羧酸
参考文献:一类含有2,4-噻唑环的化合物及其制备方法和应用
标题:一类含有2,4-噻唑环的化合物及其制备方法和应用
摘要:本申请提供一类含有2,4‑噻唑环的化合物及其制备方法和应用,该化合物如式x:A为吡唑并嘧啶或者吲哚;Z为无或羰基;X为o或s;Y为‑o‑,‑nh‑或r1为氢或c1‑6烷基;R2选自c1‑c3烷基,C5‑c15烯基,炔基,5‑10元杂环基,C6‑c12芳基,5‑12元杂芳基,甾醇基和5‑10元环烷基;Y与r2相连,或y与r2成环;R3选自氢,卤素,氨基,羟基,乙酰基,3‑10元杂环基,C6‑c12芳基,5‑12元杂芳基,3‑10元环烷基,酯基,羧基,三卤甲基和金刚烷基;R2或r3是未被取代或者是被选自c1‑c6烷基,羟基,卤素,三卤甲基,羧基,苯基所取代的;R2为c1‑c3烷基时,R3不为氢.

专利信息

专利号:US-8471006-B2
优先权日:2003-10-31
标题:Coupling agents for peptide synthesis
发明人：CARPINO LOUIS A; XIA JUSONG; ZHANG CHONGWU; SFERDEAN CALIN DAN
权利人:CARPINO LOUIS A; XIA JUSONG; ZHANG CHONGWU; SFERDEAN CALIN DAN; UNIV MASSACHUSETTS
摘要:The present invention is directed to compounds of the formula: n nor salts thereof or N-oxides and their use in peptide synthesis.

专利号:WO-2022256358-A1
优先权日:2021-06-03
标题 :Process for preparing medicaments
发明人：STUMPF ANDREAS; LAO DAVID; ANGELAUD REMY; MARX ANDREAS
权利人:GENENTECH INC; HOFFMANN LA ROCHE; HOFFMANN LA ROCHE
摘要:The present application affords an improved preparation of 3-(5-chloro-2-(difluoromethoxy)phenyl)-1H-pyrazol-4-amine hydrochloride qhich was a useful intermediate in the synthesis of JAK inhibitors.

专利号:WO-2005070931-A1
优先权日:2004-01-14
标 题:Two-phase method for the synthesis of selected pyrazolopyrimidines

专利号:US-2018354909-A1
优先权日:2015-12-11
标题:Substituted benzimidazolium, pyrido-imidazolium, or pyrazino-imidazolium compounds as chemotherapeutics
发明人：DE BRABANDER JEF; PARADA LUIS F; LIM S KYUN; LIANG QIREN; Wang hua-yu; SHI YUFENG
权利人:UNIV TEXAS
摘要:Provided herein are compounds of the formula:(I) wherein: R1, R2, R3, R4, R5, X, A1, A2, A3, and A4 are as defined herein. In some aspects, these compounds may be used to treat cancer and other hyperproliferative disease. In some aspects, compositions, methods of treatment, and methods of synthesis are also provided herein.