专利号:US-7294743-B2 优先权日:2003-10-23 标题:Method for synthesis of acrylamide derivatives 发明人:ALGOTSSON MATTIAS; BUSSON PHILIPPE; THEVENIN NICOLAS 权利人:GE HEALTHCARE BIO SCIENCES AB 摘要:The present invention relates to a method for synthesis of an acrylamide derivative, starting with dissolving a salt of a nucleophilic amine in water to form an aqueous solution and desalting said solution with a base, comprising the following steps:n a) addition of dissolved activated acrylic acid derivative to said solution; b) acidification of aqueous phase; and c) extraction of said aqueous phase.
专利号:US-2007106090-A1 优先权日:2003-10-23 标题:Method for synthesis of acrylamide derivatives
专利号:US-7629388-B2 优先权日:2001-11-20 标题:Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion 发明人:MIKOS ANTONIOS G; TANAHASHI KAZUHIRO 权利人:UNIV RICE WILLIAM M 摘要:A cross-linkable monomer comprises a fumaric acid functional group having a first end and a second end, a first spacer group affixed to said first end and comprising at least repeating unit, a first terminal group affixed to said first spacer group, a second spacer group affixed to said second end and comprising at least one ethylene glycol repeating unit, and a second terminal group affixed to said second spacer group. A hydrogel formed by cross-linking the present monomer and a method for making the monomer. A method for forming a hydrogel, comprises the steps of a) synthesizing a copolymer of poly(propylene fumarate) (PPF) and poly(ethylene glycol (PEG) so as to produce P(PF-co-EG), b) synthesizing a PEG-tethered fumarate (PEGF), c) coupling agmatine sulfate to the PEGF to produce PEGF modified with agmatine (Agm-PEGF), and d) cross-linking the P(PF-co-EG) from step a) with Agm-PEGF from step c).
专利号:WO-2005040092-A1 优先权日:2003-10-23 标 题 :Method for synthesis of acrylamide derivatives
专利号:CA-2542206-A1 优先权日:2003-10-23 标题 :Method for synthesis of acrylamide derivatives
专利号:EP-1675818-A1 优先权日:2003-10-23 标 题 :Method for synthesis of acrylamide derivatives