CAS: 208173-19-7; 2-Fluoro-3-(Trifluoromethyl)Benzoyl Chloride
该化合物是一种芳香化合物,其特点是存在一种苯并基氯功能组,即附于苯环的碳基(C=O)组,以及芳香环上的氟原子和三氟甲基组(CF3),该化合物一般无色至黄色黄色液体或固体,视其纯度和温度而定;该化合物由于存在丙基氯功能组,具有较高的再活动性,使其在各种化学合成过程中有用,特别是在形成酯类和氨基的过程中.三氟甲基组有助于其亲耳性,并能增强化合物的生物活动.此外,氟基原子的存在往往具有独特的电子特性,影响化合物的再活动性和稳定性.在处理该物质时,必须采取安全防范措施,因为它可以是腐蚀性的,在接触水或水分时可能会释放有毒气体.
- 英文名称2-Fluoro-3-(Trifluoromethyl)Benzoyl Chloride
- 中文名称2-氟-3-(三氟甲基)苄氧基氯
- IUPAC名称2-fluoro-3-(trifluoromethyl)benzoyl chloride
- 其它别名2-Fluoro-3-(Trifluoromethyl)Benzoylchloride; 2-Fluoro-3-Trifluoromethylbenzoylchloride; 2-Fluoro-3-Trifluoromethyl Benzoyl Chloride; 2-Fluoro-3(Trifluoromethyl)Benzoyl Chloride; 2-Fluoro-3-(Trifluoromethyl)Benzoyl
- CAS编号208173-19-7
- MFCD编号:MFCD00061154
- EINECS号:632-655-9
- 分子式:C8H3ClF4O分子量:226.56
- 产品CID: 1059560
- 产品分类化学试剂 → 有机试剂 → 酰卤
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报上下游产品
CAS号115029-22-6 2-氟-3-(三氟甲基)苯甲酸 | CAS号680610-54-2 2-fluoro-N-meth...合成工艺路线路线简述
📜2-氟三氟甲苯置于正丁基锂,氯化亚砜体系中,用 四氢呋喃,正己烷,二氯甲烷,N,N-二甲基甲酰胺 用作溶剂,化学反应 5.0H,反应生成2-氟-3-(三氟甲基)苄氧基氯
参考文献:2-氟-3-三氟甲基苯胺的制备方法
标题:2-氟-3-三氟甲基苯胺的制备方法
摘要:本发明公开了一种2‑氟‑3‑三氟甲基苯胺的制备方法,利用2‑氟‑三氟甲基苯作为起始原料,通过n‑buli拔氢,二氧化碳干冰插羰得到2‑氟‑3‑三氟甲基苯甲酸;再通过dppa反应直接得到目标产物2‑氟‑3‑三氟甲基苯胺.本发明缩短了合成步骤,改善了可操作性,消除了放大效应,适合工业化生产.
海关参考信息
- 2912110000-甲醛
2912210000-苯甲醛
2903110000-一氯甲烷及氯乙烷 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9409879-B2
优先权日:2011-03-29
标 题 :Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
发明人：DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA
权利人:DAVIOUD-CHARVET ELISABETH; LANFRANCHI DON ANTOINE; JOHANN LAURE; WILLIAMS DAVID LEE; CESAR RODO ELENA; CENTRE NAT RECH SCIENT
摘要:Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and methods of their use as antimalarial or antischistosomal agents.
专利号:US-2014121238-A1
优先权日:2011-03-29
标 题:Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
专利号:WO-2012131010-A1
优先权日:2011-03-29
标 题 :Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
专利号:CN-103534238-A
优先权日:2011-03-29
标 题:Total synthesis of redox active 1, 4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistosomimetics
专利号:CN-103534238-B
优先权日:2011-03-29
标题 :Total synthesis of redox-active 1.4‑naphthoquinone and its metabolites and their therapeutic use as antimalarial and schistosicides
专利号:EP-2691372-A1
优先权日:2011-03-29
标 题 :Total synthesis of redox-active 1.4-naphthoquinones and their metabolites and their therapeutic use as antimalarial and schistomicidal agents
