CAS: 1710-98-1; 4-Tert-Butylbenzoylchloride

相似化合物

21900-62-9 939-97-9 174579-99-8

上下游产品

4-(1,1-dimethylethyl)benzoic acid 4'-t-butylacetophenone 1-bromo-4-tert-butylbenzene p-tert-butylbenzyl alcohol 1-[4-(tert-butyl)phenyl]-2-diazoethanone 2-(N-piperidinylethyl) p-tert-butylbenzoate tert-butyl-benzoic acid-(1-phenyl-2-pyrrolidino-ethyl ester); hydr°Chloride4-tert-butyl-benzoic acid-(1-phenyl-2-pyrrolidino-ethyl ester); hydr°Chloride tert-butyl-benzoic acid-(1-phenyl-2-piperidino-ethyl ester); hydr°Chloride4-tert-butyl-benzoic acid-(1-phenyl-2-piperidino-ethyl ester); hydr°Chloride

对叔丁基苯甲酸置于氯化亚砜体系中,化学反应 2.0H,反应生成对叔丁基苯甲酰氯
参考文献:Synthesis And Antifungal Activity Of Cuminic Acid Derivatives
标题:Synthesis And Antifungal Activity Of Cuminic Acid Derivatives
摘要:一系列苯甲酰胺衍生物(化合物1-29)是基于前导化合物枯酸合成得到的.化合物11的晶体结构通过单晶x射线衍射进行了表征.合成的化合物对七种植物病原真菌,即立枯丝核菌,玉蜀黍赤霉,玉蜀黍蠕孢,核盘菌,灰葡萄孢,双孢脐腐菌和葫芦脐腐菌,进行了抗真菌活性测定.初步结果表明,大多数化合物显示出显著的抗真菌活性.其中,化合物22表现出最强的活性,并且对h. Maydis,S. Sclerotiorum和b. Cinerea的抗真菌活性优于多菌灵.
Doi:10.1007/s10600-017-2212-Z

专利信息

专利号:US-10683318-B2
优先权日:2014-10-17
标 题:Scalable synthesis of reduced toxicity derivative of amphotericin B
发明人：BURKE MARTIN D; UNO BRICE E; RAKSHIT SOUVIK
权利人:UNIV ILLINOIS
摘要:Disclosed is a simplified, readily scalable series of individual methods that collectively constitute a method for the synthesis of C2′epiAmB, an efficacious and reduced-toxicity derivative of amphotericin B (AmB), beginning from AmB. Also provided are various compounds corresponding to intermediates in accordance with the series of methods.

专利号:EP-0948511-B1
优先权日:1996-12-24
标 题:Chemical synthesis of nucleosides analogs and their incorporation into polynucleotides
发明人：KARPEISKY ALEXANDER; BEIGELMAN LEONID; MATULIC-ADAMIC JASENKA
权利人:SIRNA THERAPEUTICS INC
摘要:Novel nucleosides, process for chemical synthesis of nucleosides and incorporation of the nucleosides into polynucleotides are disclosed. Also described are polynucleotides, such as antisense, TFO and nucleic acid catalysts with one or more modifications, such as 2'-O-amino, L-nucleotides and the others.

专利号:US-8778958-B2
优先权日:2008-07-10
标题 :Synthesis of metabolically stable agents for alcohol and drug abuse
发明人：CASHMAN JOHN R
权利人:CASHMAN JOHN R
摘要:The disclosed opioid-related compounds and pharmaceutical compositions thereof, are useful in a variety of applications relating to the modulation of receptors and receptor signaling within and outside the nervous system. For example, the compounds and compositions are useful in methods for the treatment of addictions and other CNS-related disorders. The disclosed compounds can be delivered or administered to a mammal including humans, alone in the form of a pharmaceutically acceptable salt or hydrolysable precursor thereof, or in the form of a pharmaceutical composition, wherein a therapeutically effective amount of a compound is mixed with suitable carriers or excipients.

专利号:US-2017233427-A1
优先权日:2014-10-17
标题 :Scalable synthesis of reduced toxicity derivative of amphotericin b

专利号:US-2019127412-A1
优先权日:2014-10-17
标题 :Scalable synthesis of reduced toxicity derivative of amphotericin b

专利号:US-2005059817-A1
优先权日:2000-09-01
标题 :Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives
发明人：BEIGELMAN LEONID; KARPEISKY ALEXANDER; SEREBRYANY VLADMIR; HAEBERLI PETER; SWEEDLER DAVID
权利人:SIRNA THERAPEUTICS INC
摘要:The present invention provides methods for the chemical synthesis of nucleosides and derivatives thereof, including 2′-amino, 2′-N-phthaloyl, 2′-O-methyl, 2′-0-silyl, 2′-O-triisopropylsilyloxymethyl, 2′-OH nucleosides, C-nucleosides, nucleoside phosphoramidites, C-nucleoside phosphoramidites, and non-nucleoside derivatives.